DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and ANGPTL7

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_066969.1	Gene:	ANGPTL7 / 10218	HGNCID:	24078	Length:	346	Species:	Homo sapiens

Alignment Length:	207	Identity:	77/207 - (37%)
Similarity:	117/207 - (56%)	Gaps:	14/207 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NGIHQLM------LPEEEPFQVTQCKTTARDWIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFI 89
            :|:::|.      .||.|.|  ...:|:...|.:||||..|.|:|.:.|..||.|||...|:|::
Human   142 SGVYKLPPDDFLGSPELEVF--CDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWL 204

  Fly    90 GLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSGTAG-DSLRYHI 153
            |.:.::.::| ||..|.::::...|...||.:..|.:.:|...|:| .:|.|:|..| |:|:||.
Human   205 GNEHIHRLSR-QPTRLRVEMEDWEGNLRYAEYSHFVLGNELNSYRL-FLGNYTGNVGNDALQYHN 267

  Fly   154 NKRFSTFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYFREGETGM-LNGIHWGRW--KFQSL 215
            |..|||.|:|||.....||....||:|::.|..|:|||:|:|.||... |:||.|..|  ...||
Human   268 NTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHNKHLDGITWYGWHGSTYSL 332

  Fly   216 TFVQIMIRPKYF 227
            ..|::.|||:.|
Human   333 KRVEMKIRPEDF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	75/203 (37%)
ANGPTL7	NP_066969.1	SMC_N	<37..>109	CDD:330553
ANGPTL7	NP_066969.1	FReD	129..341	CDD:238040	74/202 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810