DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31832 and angpt2

DIOPT Version :9

Sequence 1:	NP_723894.2	Gene:	CG31832 / 318970	FlyBaseID:	FBgn0051832	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_017949917.2	Gene:	angpt2 / 101731563	XenbaseID:	XB-GENE-487765	Length:	498	Species:	Xenopus tropicalis

Alignment Length:	204	Identity:	80/204 - (39%)
Similarity:	116/204 - (56%)	Gaps:	9/204 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NGIHQLMLPEEEPFQVTQC--KTTARDWIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFIGLQK 93
            |||:.|.:........|.|  ||....|.:||:|.||||:|:::|..||.|||||.||:::|.:.
Frog   297 NGIYTLTILNTTDQAKTYCDMKTDGGGWTIIQKRFDGSVDFHRTWKEYKKGFGDPAGEYWLGNEL 361

  Fly    94 LYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSGTAG--DSLRYHINKR 156
            :..:|..|.:.|.|||:...|...::.::.|.:.:|.:.|::...| |:||||  :|:....|.
Frog   362 VSQLTNLQKYVLKIQLRDWEGNQAFSLYEHFYLGNEAQKYRINLKG-YTGTAGKINSISQPGND- 424

  Fly   157 FSTFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYFREGE-TGMLNGIHWGRWKFQ--SLTFV 218
            |||.|.|||:....|:....|||||.:|..|:|||:|:..|: |...|||.|..||..  ||...
Frog   425 FSTKDADNDKCICKCSQMATGGWWFDACGPSNLNGMYYSMGQNTNKFNGIKWYYWKGSGYSLKAT 489

  Fly   219 QIMIRPKYF 227
            .:||||..|
Frog   490 TMMIRPVDF 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31832	NP_723894.2	FReD	28..225	CDD:238040	78/200 (39%)
angpt2	XP_017949917.2	Mplasa_alph_rch	<80..>249	CDD:275316
angpt2	XP_017949917.2	FBG	282..496	CDD:214548	78/200 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910