Protein Alignment CG31827 and PRSS21

DIOPT Version :10

• Sequence 1: NP_723923.1
• Gene: CG31827 / 318965
• FlyBaseID: FBgn0051827
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 70/263 - (26%)
• Similarity: 114/263 - (43%)
• Gaps: 36/263 - (13%)

  Fly    50 AKPAEFPWTIAVIHNRSLVGGGSLITPDIVLTAAHRIFNKDVEDIVVSAGEW--EYG--SALEKY 110
            |:...:||..::....|.|.|.||::....|||||..  :...|:...:| |  ::|  :::..:
Human    48 AELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCF--ETYSDLSDPSG-WMVQFGQLTSMPSF 109

  Fly   111 PFEEAFVLKMVIHKSFNYQRGANN----LALLFLDREFPLTYKINTICLPTQKRSLSS-TRCIVA 170
            ...:|:..:..:...:...|...|    :||:.|......|..|..|||........: |.|.|.
Human   110 WSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVT 174

  Fly   171 GWGKYQFSDT----HYGGVLKKIDLPIVPRHICQD-----QLRKTRLGQNYTLPRGLICAG-GEK 225
            |||..:..:.    |   .|:::.:.|:...:|..     ..||...|.       ::||| .:.
Human   175 GWGYIKEDEALPSPH---TLQEVQVAIINNSMCNHLFLKYSFRKDIFGD-------MVCAGNAQG 229

  Fly   226 DNDACTGDGGGALFCPMTEDPKQFEQIGIVNWGVGCKEKNVPATYTDVFEFKPWIVQQIKEN-LY 289
            ..|||.||.||.|.|   .....:.|||:|:|||||...|.|..||::.....||.:.:.:: :.
Human   230 GKDACFGDSGGPLAC---NKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQSGMS 291

  Fly   290 TPD 292
            .||
Human   292 QPD 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31827	NP_723923.1	Tryp_SPc	50..280	CDD:214473	66/248 (27%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	68/250 (27%)