DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31815 and CG4631

DIOPT Version :9

Sequence 1:	NP_723979.1	Gene:	CG31815 / 318959	FlyBaseID:	FBgn0051815	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_609799.1	Gene:	CG4631 / 34988	FlyBaseID:	FBgn0032590	Length:	796	Species:	Drosophila melanogaster

Alignment Length:	470	Identity:	111/470 - (23%)
Similarity:	175/470 - (37%)	Gaps:	102/470 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MRKICC----------SLTANFPWTSKIVSI-----GQKQPSRSTCLSQEHCLWRQRNQMEIEQL 52
            |...||          :....||...::.|.     |:|  :.|.|:|.|. .|.|||...|:.|
  Fly     1 MNSCCCRSHSDRTNPMACLPQFPRLQRVQSCRPFLEGRK--AASCCVSGER-RWGQRNGCMIQVL 62

  Fly    53 AKLVGFQPDEIDGFLFNLSLRNYSDLLKYKECGWNGCNVPLCYPYVCDRYMAIFDHRGNLRSPIH 117
            ||:|......:..||..|:|:.::.:|.....|||...||...|.:|:.|..|||..||:|..|.
  Fly    63 AKMVNKSSSTVCQFLHQLTLQVFARILYPLMLGWNTLKVPFVIPDICELYYGIFDECGNIRGSIP 127

  Fly   118 ARSLKSLLPLLLDYLNGDSPNDRKDSPIYEAYPDEHQAKCRSNIEQSDLEAMSSSDWISQLLGNP 182
            .|:|..|:.::..:||......:..:          .:.|||  :..||..:.|..:..:....|
  Fly   128 TRTLLILISMIQYFLNLPKRCGQNSA----------CSGCRS--QTDDLRNIHSPGYCGKNAMTP 180

  Fly   183 SESKREKTGKKTEKPQPVMRSELESELESESEMEKKKRKNKTFGRQSVFLNDELALAYAKSYDYA 247
            . |.|..|.|...|...|.........|...:::.             :.:||     :..|.||
  Fly   181 F-SGRGITEKGPSKGSDVWAGLKRLGYERRGDLDS-------------YPSDE-----SIPYGYA 226

  Fly   248 EYLMKTLGRHRFRDSYIGP--VGDLRTTRTHILIRDLIARKGMNINEKNLRKALKKVDLEWKGTT 310
            .        ||.      |  .|..|..|:.|| .....|.|.      :|..:...:|| ....
  Fly   227 P--------HRC------PCQAGSPRIQRSGIL-NPYANRPGA------MRSLVCAEELE-SSML 269

  Fly   311 RADYKREM-------KTAQ-----EISRLYNVIVQTPSDEPIPWRIIGKVRENYPKVPKASKSPR 363
            .:||.:::       |.||     .||.||..:||.....    ::....|...|:|...:::..
  Fly   270 DSDYNQQIPMAPISPKAAQIIHINHISNLYAAVVQNQHTR----QLFADGRPPRPRVRPCTENQN 330

  Fly   364 KYLADQDAMVFHEPFDHKKNWTWQRRQSKRTIRNSNYKFSTTRIKPYISRSMKQEIEPLKDEASI 428
            ::   ....:..||:.:...|:|..|..:|.||     ..:..:...|.|..:|   ||.:|  .
  Fly   331 RF---SGGFMMPEPYFNGMPWSWLHRDPQRMIR-----LPSGGLPLEIPRYRRQ---PLDEE--Y 382

  Fly   429 HSSLSDRARLQKRES 443
            ||..|....|.:|::
  Fly   383 HSFKSKYEHLSRRDN 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31815	NP_723979.1	DUF4778	35..329	CDD:292627	76/307 (25%)
CG4631	NP_609799.1	DUF4778	46..>241	CDD:292627	60/240 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468783
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0016727
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.930