DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and Chl1

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	XP_038964701.1	Gene:	Chl1 / 89828	RGDID:	620122	Length:	1224	Species:	Rattus norvegicus

Alignment Length:	552	Identity:	104/552 - (18%)
Similarity:	170/552 - (30%)	Gaps:	192/552 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 PRFAEPIANV------TVSVGRDALMACVVENLKGYKVAWVRVDTQ-----TILSIHHNVISQNS 127
            |:...|.|.:      ||..|...|:.|..|.|...::.|.::.::     ..:.||...
  Rat   250 PKLLLPPAQIGSASSKTVLKGDTLLLECFAEGLPTPQIEWSKLGSELPKGRATIEIHEKT----- 309

  Fly   128 RISLTYNDHRSWYLHIKEVEETDRGWYMCQVNT--------------DPMRSRKGYLQVVVPPII 178
                         |.|:.|...|||.|.|..|.              :|.|.:|
  Rat   310 -------------LKIENVSYQDRGNYRCTANNLLGKASHDFHVIVEEPPRWKK----------- 350

  Fly   179 VEGLTSNDMVVREGQNISLVCKARGYPEPYVMWRREDGEEMLIGGEHV-------NVVDGELLHI 236
                .....|...|.|..|:|:|.|.|:|.:.||        :.|..:       :|:....:..
  Rat   351 ----KPQSAVYSTGSNGILLCEAEGEPQPTIKWR--------VNGLPIENHPFPGDVMFPREISF 403

  Fly   237 TKVSRLHMAAYLCVASNGVPPSISKRVHLR-VQFPPMLSIPNQLEGAY---LGQDVILECHTEAY 297
            |.:...|.|.|.|.||| :..:|....::. |...|::...|  |..|   :|....|.|...|.
  Rat   404 TNLQPNHTAVYQCEASN-IHGTILANANIDVVDVVPLIQTKN--EENYETVVGYSAFLHCEYFAS 465

  Fly   298 PASINYWTTERGDMIISDTSR--AGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLG 360
            |.:...|.       ::|.:.  .|.:|.|....:       |:|......|.|:|.|...|::|
  Rat   466 PKATVVWE-------VADETHPLEGGRYHTHENGT-------LEIERTTEEDAGSYSCWVDNTMG 516

  Fly   361 ETDGNIKLDEMPTPTTAIISEMSLLNRSY----------DGKRRHRNKFD---SANALPDYGVEE 412
            :......||........:..:...:.:|:          |...:|..|..   ...|....|.|:
  Rat   517 KAVITANLDIRNATKLRVFPKNPRIPKSHVLELYCESQCDSHLKHSLKLSWSKDGEAFEMNGTED 581

  Fly   413 WR---DGA-------QGNNAGNNGDNNQTPVRNPPGAFHNSAGSLAQHNLLAKIMLGIKTQSFGI 467
            .|   |||       .|.:.|....:.||.:.:..|                      |||
  Rat   582 GRIVIDGANLTISNISGEDQGIYSCSAQTALDSTSG----------------------KTQ---- 620

  Fly   468 FKRLSSSLPLAAGQSFLWLSTLSLVSAPSRWRMSNVENRPNSPETVVNNDTAAECWETRSHCVSE 532
                              ::.|.:...|....:|..:||           :....|        |
  Rat   621 ------------------VTVLGVPDPPRNLLLSERQNR-----------SVRLSW--------E 648

  Fly   533 SNNNNNSRIT----------QRPPMWARHLRI 554
            :.:::||:|:          :.|..|....|:
  Rat   649 AGDDHNSKISEYIVEFEGNREEPGKWEELTRV 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	23/116 (20%)
		IG_like	82..174	CDD:214653	22/116 (19%)
		IG_like	184..267	CDD:214653	22/90 (24%)
		IGc2	191..255	CDD:197706	20/70 (29%)
		IG_like	282..368	CDD:214653	19/90 (21%)
		Ig	288..367	CDD:143165	17/80 (21%)
Chl1	XP_038964701.1	Ig	34..125	CDD:416386
		Ig strand A	34..38	CDD:409353
		Ig strand A'	43..47	CDD:409353
		Ig strand B	52..59	CDD:409353
		Ig strand C	65..70	CDD:409353
		Ig strand C'	73..75	CDD:409353
		Ig strand D	81..84	CDD:409353
		Ig strand E	89..93	CDD:409353
		Ig strand F	104..112	CDD:409353
		Ig strand G	115..125	CDD:409353
		IgI_2_L1-CAM_like	134..224	CDD:409432
		Ig strand B	148..152	CDD:409432
		Ig strand C	162..166	CDD:409432
		Ig strand E	185..189	CDD:409432
		Ig strand F	200..205	CDD:409432
		Ig strand G	216..219	CDD:409432
		Ig	261..343	CDD:416386	19/99 (19%)
		Ig strand B	273..277	CDD:409353	1/3 (33%)
		Ig strand C	286..290	CDD:409353	0/3 (0%)
		Ig strand E	308..312	CDD:409353	1/21 (5%)
		Ig strand F	322..327	CDD:409353	2/4 (50%)
		Ig strand G	335..338	CDD:409353	0/2 (0%)
		Ig4_L1-NrCAM_like	347..434	CDD:409367	24/110 (22%)
		Ig strand B	363..367	CDD:409367	1/3 (33%)
		Ig strand C	376..380	CDD:409367	0/3 (0%)
		Ig strand E	399..403	CDD:409367	0/3 (0%)
		Ig strand F	413..418	CDD:409367	2/4 (50%)
		Ig strand G	426..429	CDD:409367	0/2 (0%)
		Ig	447..524	CDD:416386	19/90 (21%)
		Ig strand A'	447..451	CDD:409353	1/3 (33%)
		Ig strand B	454..463	CDD:409353	2/8 (25%)
		Ig strand C	469..474	CDD:409353	1/11 (9%)
		Ig strand C'	477..480	CDD:409353	0/2 (0%)
		Ig strand D	485..490	CDD:409353	2/4 (50%)
		Ig strand E	491..498	CDD:409353	2/13 (15%)
		Ig strand F	505..513	CDD:409353	3/7 (43%)
		Ig strand G	516..524	CDD:409353	1/7 (14%)
		Ig	528..627	CDD:416386	20/142 (14%)
		Ig strand A	528..534	CDD:409353	0/5 (0%)
		Ig strand A'	537..542	CDD:409353	0/4 (0%)
		Ig strand B	545..553	CDD:409353	0/7 (0%)
		Ig strand C	564..568	CDD:409353	1/3 (33%)
		Ig strand D	583..586	CDD:409353	1/2 (50%)
		Ig strand E	589..593	CDD:409353	1/3 (33%)
		Ig strand F	602..609	CDD:409353	1/6 (17%)
		Ig strand G	616..620	CDD:409353	2/25 (8%)
		FN3	627..716	CDD:238020	12/73 (16%)
		fn3	730..811	CDD:394996
		FN3	832..926	CDD:238020
		FN3	931..1026	CDD:238020
		Bravo_FIGEY	1120..1201	CDD:404722
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12231
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100