DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and ntm

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	XP_021334871.1	Gene:	ntm / 678534	ZFINID:	ZDB-GENE-060421-6020	Length:	380	Species:	Danio rerio

Alignment Length:	413	Identity:	108/413 - (26%)
Similarity:	181/413 - (43%)	Gaps:	78/413 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 TQQTAQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNS 127
            :|..:|.|:      :.:.|:|:..|....::|...:...: .||  ::..:||....:..|.:.
Zfish    31 SQGESQSDN------KQMDNITIRQGETLFLSCSQGDFVTH-TAW--LNRSSILYAGEDKWSVDP 86

  Fly   128 RISLTYNDHRSWYLHIKEVEETDRGWYMCQVNTDPM-RSRKGYLQVVVPPIIVEGLTSNDMVVRE 191
            |:||.......:.:.|::|:.||.|.|:|.|.|... |:...::.|.|||.||.  .|.|:||.|
Zfish    87 RVSLVTLSQEEFTIKIEDVDVTDEGQYICAVQTSSRPRTTSVHIIVQVPPKIVN--LSRDLVVNE 149

  Fly   192 GQNISLVCKARGYPEPYVMWRREDGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVP 256
            |.|::|:|.|.|.|||.::||.:...:..:..      |.|:|.|..:||.....|.|.|:|.:.
Zfish   150 GSNVTLMCLANGKPEPAIVWRMKSPSDDSLSS------DSEVLDIPFISRYRAGVYECTAANDIA 208

  Fly   257 PSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDTSRAGD 321
            .. ::.|.|.|.:.|.:|....: |..|||..:|:|..:|.|.:...|  .|.|..|.: ...|.
Zfish   209 VD-TQTVELTVNYAPSVSDGRDV-GVTLGQRGVLQCEADAVPEADFEW--YRDDRRIFN-GLDGI 268

  Fly   322 KYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAIISEM---- 382
            :.|....:|      :|....|...|:|.|.|||.|.||..:.:..|.|:..||::.:.::
Zfish   269 EIEAAGALS------RLTFFNVSEADYGNYTCVAINKLGSANTSFVLYEIIEPTSSTLLQVETSP 327

  Fly   383 SLLNRSYDGKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNGDNNQTPVRNP----PGAFHN- 442
            |:|..:                                    :.|..|||::|.    |||..:
Zfish   328 SVLEMT------------------------------------SSDLEQTPLQNDLWEGPGAVQDG 356

  Fly   443 SAGSLAQHN----LLAKIMLGIK 461
            ::|:....|    |:|.:.|.:|
Zfish   357 NSGTSTVFNPFCLLIAILQLLLK 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	22/92 (24%)
		IG_like	82..174	CDD:214653	23/92 (25%)
		IG_like	184..267	CDD:214653	28/82 (34%)
		IGc2	191..255	CDD:197706	22/63 (35%)
		IG_like	282..368	CDD:214653	25/85 (29%)
		Ig	288..367	CDD:143165	22/78 (28%)
ntm	XP_021334871.1	Ig	44..132	CDD:325142	22/90 (24%)
		Ig_3	135..205	CDD:316449	29/77 (38%)
		I-set	228..309	CDD:333254	26/90 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576329
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.880