DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and Pdcd1lg2

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_067371.1	Gene:	Pdcd1lg2 / 58205	MGIID:	1930125	Length:	247	Species:	Mus musculus

Alignment Length:	167	Identity:	43/167 - (25%)
Similarity:	67/167 - (40%)	Gaps:	23/167 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 TVSVGRDALMACVVE-----NLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYND---HRSWY 140
            ||.||....:.|..:     .|:|.:.:..:|:..|.|        |:.|.:|....   .::.:
Mouse    31 TVDVGSSVSLECDFDRRECTELEGIRASLQKVENDTSL--------QSERATLLEEQLPLGKALF 87

  Fly   141 LHIKEVEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARGYP 205
             ||..|:..|.|.|.|.|........| ||.|.|....:. :.:..:.|.....:.|.|:|||||
Mouse    88 -HIPSVQVRDSGQYRCLVICGAAWDYK-YLTVKVKASYMR-IDTRILEVPGTGEVQLTCQARGYP 149

  Fly   206 EPYVMWRREDGEEMLIGGEHVNVVDGELLHITKVSRL 242
            ...|.|:   ...:.....|:...:| |..:|.|.||
Mouse   150 LAEVSWQ---NVSVPANTSHIRTPEG-LYQVTSVLRL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	24/95 (25%)
		IG_like	82..174	CDD:214653	25/97 (26%)
		IG_like	184..267	CDD:214653	17/59 (29%)
		IGc2	191..255	CDD:197706	16/52 (31%)
		IG_like	282..368	CDD:214653
		Ig	288..367	CDD:143165
Pdcd1lg2	NP_067371.1	IG_like	28..119	CDD:214653	25/97 (26%)
Pdcd1lg2	NP_067371.1	Ig	130..192	CDD:299845	17/57 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000