DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and CG34353

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001287571.1	Gene:	CG34353 / 5740590	FlyBaseID:	FBgn0085382	Length:	581	Species:	Drosophila melanogaster

Alignment Length:	380	Identity:	106/380 - (27%)
Similarity:	162/380 - (42%)	Gaps:	68/380 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 PRFAEPIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYNDHRS 138
            |.|...........|...::.|.|.|...|.|||.|  ...||:.....::.:.|:.|.    ..
  Fly    86 PMFISRSETFKFITGETIVLPCEVANTDTYVVAWKR--GIAILTAGSVKVTPDPRVRLV----NG 144

  Fly   139 WYLHIKEVEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARG 203
            :.|.|::...||.|.|:||:.|...|.....::::|||.|....|...:.|::|.::.:.|.|.|
  Fly   145 FNLQIRDALPTDAGDYICQIATMDPREITHTVEILVPPRIHHISTGGHLQVKKGSSVRIECSATG 209

  Fly   204 YPEPYVMWRRE-----DGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRV 263
            .|.|.|.|.|:     :|||.|    |.:|     |.|..|.|.....|:|.|:|.|....|.:|
  Fly   210 NPMPNVTWSRKNNILPNGEEKL----HSHV-----LSIENVDRHKGGVYICTANNRVGQPASSQV 265

  Fly   264 HLRVQFPPMLSIPNQLEGAYLGQDVILEC--HTEAYPASINYW--------TTERGDMIISDTSR 318
            .|.|.|.|.:|:...:..:..|.:..|.|  |.|..|..|  |        ||||..|
  Fly   266 VLHVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVI--WFKDTMQLDTTERHIM------- 321

  Fly   319 AGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAIISEMS 383
                 ||..  |.:|    |.||.|.|.|||.|.|||:|.||:....::|.  ..|..|:.:...
  Fly   322 -----ETRG--SRHT----LIIRKVHPQDFGNYSCVAENQLGKARKTLQLS--GKPNVAVFNSPP 373

  Fly   384 LLNRSYDGKRRHRNKF------DSANALPDYGVEEWRDGAQGNN-AGNNGDNNQT 431
            :        .::::::      ||.:.:.:|.: .:|...||:. .||..|::.:
  Fly   374 I--------SQYKDRYNISWAVDSHSPIEEYKL-SFRKLPQGHEVVGNAIDSSSS 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	23/91 (25%)
		IG_like	82..174	CDD:214653	23/91 (25%)
		IG_like	184..267	CDD:214653	28/87 (32%)
		IGc2	191..255	CDD:197706	23/68 (34%)
		IG_like	282..368	CDD:214653	32/95 (34%)
		Ig	288..367	CDD:143165	31/88 (35%)
CG34353	NP_001287571.1	IG_like	100..180	CDD:214653	23/85 (27%)
		Ig	103..177	CDD:143165	22/79 (28%)
		IG_like	191..269	CDD:214653	28/86 (33%)
		IGc2	198..258	CDD:197706	23/68 (34%)
		I-set	273..360	CDD:254352	34/106 (32%)
		Ig	290..359	CDD:143165	31/88 (35%)
		FN3	<466..524	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810