DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and aebp1b

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio

Alignment Length:	378	Identity:	84/378 - (22%)
Similarity:	128/378 - (33%)	Gaps:	127/378 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 SWYL-----HIK-EVEETDRGWYMCQVNTDPMRSRKGYLQV-VVPPIIVEGLTSNDMVVREGQNI 195
            ||.:     |.| |:..|||..::...|   :.|.:..||| ::||.         ..:..||:.
Zfish    21 SWEVNGLTEHSKSEISHTDREQHVEDRN---VTSVEDLLQVKIIPPY---------ATIEVGQHK 73

  Fly   196 SLVCKARGYPEPYVMWRREDGEEMLIGGEHVNVV---DGELLHITKVSRLHM---AAYLCVASNG 254
            .|:||... ....:.|...:||::|.  :|.|:.   .|.:|....|...::   ..|.|||:||
Zfish    74 QLLCKVSS-DAKNINWVSPNGEKVLT--KHGNLKVHNHGSVLSSLTVLNANLNNAGIYKCVATNG 135

  Fly   255 VPPS--------ISKRV---------HLRVQFP-----PMLSIP--------------------- 276
            ...|        |.||:         ..|::.|     |..|.|
Zfish   136 DTESQATVKLDIILKRMRRDTDRKGREKRLKEPKPSKKPKASKPTKKPKSEKKGKGEKGGKKKGK 200

  Fly   277 -NQLEGAYLGQDVILECHT------EAY-PASINYWTTERGDMIISDTSRAGDKYETTSTVSGYT 333
             |:.|...:....:....|      |.| |....||..   |.....|:.|    .||:|.:..|
Zfish   201 KNREESTTVATTTVAPTTTVPMEYEEFYDPEPDQYWDE---DFPAETTTVA----RTTTTPTEKT 258

  Fly   334 K--------YMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAIISEMSLLNRSYD 390
            |        |.:       |:.:..|              .|:|| |||||::|:.....:..|.
Zfish   259 KDFIPDMDEYSQ-------PDSYDDY--------------WKVDE-PTPTTSVIAGRPADDDDYW 301

  Fly   391 GKRRHRNKFDSANALPDYGVEEWRDGAQGNNAGNNGDNNQTPVRNPPGAFHNS 443
            ..|    ..:....||      :.||.:.::..|:.....|.....| .|.||
Zfish   302 DAR----SVEMVENLP------FPDGKEISSTDNDWQYTTTEEPTVP-PFENS 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	11/39 (28%)
		IG_like	82..174	CDD:214653	13/42 (31%)
		IG_like	184..267	CDD:214653	24/105 (23%)
		IGc2	191..255	CDD:197706	19/69 (28%)
		IG_like	282..368	CDD:214653	17/100 (17%)
		Ig	288..367	CDD:143165	17/93 (18%)
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	26/102 (25%)
		IG_like	62..145	CDD:214653	23/94 (24%)
		FA58C	402..555	CDD:238014
		FA58C	403..556	CDD:214572
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900