DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and dpr6

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001287018.1	Gene:	dpr6 / 50296	FlyBaseID:	FBgn0040823	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	99/385 - (25%)
Similarity:	149/385 - (38%)	Gaps:	99/385 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LMTATPTLAEIPSKGKHTRLDTQQTAQEDSDFPRFAEPI------ANVTVSVGRDALMACVVENL 100
            |:|.|||    |.:.. ..|.|..||.  ...|::.||.      .|||..:|:.|.::|.|.||
  Fly    43 LLTTTPT----PGQAA-LLLPTAPTAA--YTHPKWMEPYFDPSTPRNVTALMGKSAYLSCRVRNL 100

  Fly   101 KGYKVAWVRVDTQTILSIHHNVISQNSRISLTYN-DHRSWYLHIKEVEETDRGWYMCQVNTDPMR 164
            ....|:|:|.....||::.....:.:.|...|:: |...|.|.||..::.|.|.|.||::|.|:|
  Fly   101 ANKTVSWIRHRDIHILTVGSYTYTSDQRFQATHHQDTEDWTLQIKWAQKRDAGMYECQISTQPVR 165

  Fly   165 SRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARGYPEP--YVMWRREDGEEML-----IG 222
            |....|.||||...:.|  ..|:.|.:|..|:|.|..:..|||  |:.|...  ||::     .|
  Fly   166 SYFVRLNVVVPTATILG--GPDLHVDKGSTINLTCTVKFSPEPPAYIFWYHH--EEVINYDSSRG 226

  Fly   223 GEHVNVVDGEL----LHITKVSRLHMAAYLCVASNGVPPSISKRVHLRVQFPPMLSIPNQLEGAY 283
            |..|....|::    |.|..........|.|..||....|:  |||       :|::...:.|.:
  Fly   227 GVSVITEKGDVTTSFLLIQNADLADSGKYSCAPSNADVASV--RVH-------VLNVRAIISGEH 282

  Fly   284 ---------------------LGQDVILECH-----TEAYPASIN----------------YWTT 306
                                 ||   ::.|:     :.|.|||:.                ..||
  Fly   283 PEAMQTGSSGCQYNWLTIVLLLG---LVLCYSSQQCSSAVPASLTSSLPLPSQLPLPAAAAATTT 344

  Fly   307 ERGDMIISDTSRAGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNI 366
            ..|:...|::..|......|:|.:..|:                .||.|..|..:|.|.:
  Fly   345 ATGESASSESVTAARASAATTTTTTATR----------------KRCPAVKSCRQTAGRV 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	31/98 (32%)
		IG_like	82..174	CDD:214653	32/92 (35%)
		IG_like	184..267	CDD:214653	27/93 (29%)
		IGc2	191..255	CDD:197706	21/74 (28%)
		IG_like	282..368	CDD:214653	21/127 (17%)
		Ig	288..367	CDD:143165	19/100 (19%)
dpr6	NP_001287018.1	V-set	79..174	CDD:284989	31/94 (33%)
		IG_like	80..175	CDD:214653	32/94 (34%)
		IG_like	184..271	CDD:214653	27/97 (28%)
		IGc2	191..262	CDD:197706	20/72 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810