DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-kappa and dpr11

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001262320.1	Gene:	dpr11 / 40800	FlyBaseID:	FBgn0053202	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	75/265 - (28%)
Similarity:	105/265 - (39%)	Gaps:	45/265 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TIIATAAVTML----------MTATPTLAEIPSKGKHTRLDTQQTAQEDSDFPRFAEP------I 80
            |..|:||.|.:          .||..:||::.|        ....|...|......||      .
  Fly    68 TSSASAASTAISSDESGDPSSATAFSSLAQVSS--------LLPEASALSATSGLVEPYLDGYAT 124

  Fly    81 ANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYNDHRSWYLHIKE 145
            :|||..:|..|.:.|.|:.|....|:|:|:....||::...|...:.|........:.|.|.||.
  Fly   125 SNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHILTVDRAVFIADQRFLAIKQPDKYWTLQIKY 189

  Fly   146 VEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARGYPEP--Y 208
            |:..|.|.|.|||:|:|..|.:..||||||.  .|.|...|..|:.|.|:.|.|..||..||  :
  Fly   190 VQARDAGSYECQVSTEPKVSARVQLQVVVPR--TEILGEPDRYVKAGSNVVLRCIVRGALEPPTF 252

  Fly   209 VMWRREDGEEMLIGG--EHVNVVDGEL-------------LHITKVSRLHMAAYLCVASNGVPPS 258
            :||..  |.|.|...  .|...:|..|             |.|....:.....|.|..||....:
  Fly   253 IMWYH--GAEQLAADSRRHRTQLDPNLPEASGEGQSTIGSLIIESAKKRDTGNYTCSPSNSPSAT 315

  Fly   259 ISKRV 263
            ::..:
  Fly   316 VTLNI 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	30/91 (33%)
		IG_like	82..174	CDD:214653	32/91 (35%)
		IG_like	184..267	CDD:214653	24/97 (25%)
		IGc2	191..255	CDD:197706	22/80 (28%)
		IG_like	282..368	CDD:214653
		Ig	288..367	CDD:143165
dpr11	NP_001262320.1	I-set	125..216	CDD:254352	30/90 (33%)
		Ig	127..217	CDD:299845	30/89 (34%)
		IG_like	227..320	CDD:214653	24/94 (26%)
		IGc2	234..311	CDD:197706	21/78 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810