DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-kappa and Lac

DIOPT Version :9

Sequence 1:NP_723828.1 Gene:DIP-kappa / 318958 FlyBaseID:FBgn0051814 Length:672 Species:Drosophila melanogaster
Sequence 2:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster


Alignment Length:353 Identity:106/353 - (30%)
Similarity:162/353 - (45%) Gaps:51/353 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 LAITIIATAAVTMLMTATPTLAEIPSKGKHTRLDTQQTAQEDSDFPRFAEPIANVTVSVGRDALM 93
            |||.:..|     |...|||::.|          ||:..::                 :|.....
  Fly    16 LAIFVQQT-----LAQRTPTISYI----------TQEQIKD-----------------IGGTVEF 48

  Fly    94 ACVVENLKGYKVAWVRVDTQTI-LSIHHNVISQNSRISLTYNDHRSWY-LHIKEVEETDRGWYMC 156
            .|.|:..|.|.|.:::.|:..: ||....::.::||.||.|:.:.|.| |.||:::|||.|.|.|
  Fly    49 DCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTC 113

  Fly   157 QV--NTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARGYPEPYVMWRREDGEEM 219
            ||  :|....|.:..|.|..||:|.:..|.: :|..||..:.:.|.|.|||.|.:.||||:  ..
  Fly   114 QVVISTVHKVSAEVKLSVRRPPVISDNSTQS-VVASEGSEVQMECYASGYPTPTITWRREN--NA 175

  Fly   220 LIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLRVQFPPMLSIPNQLEGAYL 284
            ::..:....| |..|.|..|.:.....|.|||.|||.....:.:::.|:|.|::::|....|..|
  Fly   176 ILPTDSATYV-GNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQAL 239

  Fly   285 GQDVILECHTEAYPASINYWTTERGDMIISDTSRAGDKYETTS---TVSGYTKYMKLKIRAVGPN 346
            ..|:.||||.||||.....||.:       |...|.:::.:.|   |...||. ..|::..|...
  Fly   240 QYDMDLECHIEAYPPPAIVWTKD-------DIQLANNQHYSISHFATADEYTD-STLRVITVEKR 296

  Fly   347 DFGTYRCVAKNSLGETDGNIKLDEMPTP 374
            .:|.|.|.|.|..||.:..:.|.|...|
  Fly   297 QYGDYVCKATNRFGEAEARVNLFETIIP 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-kappaNP_723828.1 Ig 80..172 CDD:299845 30/95 (32%)
IG_like 82..174 CDD:214653 31/95 (33%)
IG_like 184..267 CDD:214653 25/82 (30%)
IGc2 191..255 CDD:197706 22/63 (35%)
IG_like 282..368 CDD:214653 27/88 (31%)
Ig 288..367 CDD:143165 25/81 (31%)
LacNP_523713.2 IG_like 36..131 CDD:214653 31/111 (28%)
FR1 37..50 CDD:409353 1/29 (3%)
Ig strand A' 37..42 CDD:409353 0/21 (0%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 2/7 (29%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 2/13 (15%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 15/30 (50%)
Ig strand D 84..90 CDD:409353 3/5 (60%)
Ig strand E 94..102 CDD:409353 4/7 (57%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 26/77 (34%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 29/98 (30%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442831
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - otm40772
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
87.850

Return to query results.
Submit another query.