DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-kappa and Prtg

DIOPT Version :9

Sequence 1:NP_723828.1 Gene:DIP-kappa / 318958 FlyBaseID:FBgn0051814 Length:672 Species:Drosophila melanogaster
Sequence 2:NP_001032740.2 Gene:Prtg / 315806 RGDID:1307157 Length:1193 Species:Rattus norvegicus


Alignment Length:464 Identity:84/464 - (18%)
Similarity:141/464 - (30%) Gaps:188/464 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 MLMTATPTLAEIPSKGKHTRLDTQQTAQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKV 105
            :|:...|.|..:|.....:.|...:..|:             .||:......:.|........||
  Rat    13 LLLLLLPPLGSVPGVWSFSELFFMKEPQD-------------ATVTRKDPVFLDCQAHGEGPIKV 64

  Fly   106 AWVRVDTQTILSIHHNVISQNSRISLTYNDHRSWYLHIKEV-----EETDRGWYM---------- 155
            .|::...:         :|:|.||.:..|..    |:|.|.     |::|.|:|.          
  Rat    65 TWLKNGAK---------LSENKRIQVLSNGS----LYISEAEGRRGEQSDEGFYQCLAVNKYGAI 116

  Fly   156 ---------------------------------CQVNTDP----------------MRSR----- 166
                                             |::::.|                |.||     
  Rat   117 LSQKAHLTLSTISAFEVHPVSTEVPEGGVARFSCKISSTPPAVITWEFNRTALPMTMDSRVTALP 181

  Fly   167 KGYLQV------------------------------VVP---------PIIVEGLTSNDMVVREG 192
            .|.||:                              :||         |.|:  .:..::.....
  Rat   182 SGVLQIYDAGPEDAGKYRCVAATHAHKRKSMEASLTIVPANETRSFYMPTII--ASPQNVTASLH 244

  Fly   193 QNISLVCKARGYPEPYVMWRREDGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNG--- 254
            |.:.|.|.|.|||:|.:.|.|.|.:.:.:....| :.:|.|: |:.|...|...|:|.|:..   
  Rat   245 QTVVLECMATGYPKPIISWSRLDHKSIDVFNTRV-LGNGNLI-ISDVKLQHAGVYVCRATTPGTR 307

  Fly   255 ------------VPPSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTE 307
                        .|||.       |::|..|:.|......::       |..|..|:....|.  
  Rat   308 NFTVAMATLTVLAPPSF-------VEWPESLTRPRAGTARFV-------CQAEGIPSPKMSWL-- 356

  Fly   308 RGDMIISDTSRAGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMP 372
                      :.|.:..:...:..|..  ||.|..:.|.|...|:|:|:||.|......:|    
  Rat   357 ----------KNGRRIHSNGRIKMYNS--KLVINQIIPEDDAIYQCMAENSQGSVLSRARL---- 405

  Fly   373 TPTTAIISE 381
               |.::||
  Rat   406 ---TVVMSE 411

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-kappaNP_723828.1 Ig 80..172 CDD:299845 25/160 (16%)
IG_like 82..174 CDD:214653 26/190 (14%)
IG_like 184..267 CDD:214653 23/97 (24%)
IGc2 191..255 CDD:197706 20/78 (26%)
IG_like 282..368 CDD:214653 17/85 (20%)
Ig 288..367 CDD:143165 17/78 (22%)
PrtgNP_001032740.2 Ig 32..124 CDD:416386 20/117 (17%)
Ig strand A 32..35 CDD:409353 1/2 (50%)
Ig strand A' 38..44 CDD:409353 1/18 (6%)
Ig strand B 48..58 CDD:409353 1/9 (11%)
Ig strand C 62..68 CDD:409353 3/5 (60%)
Ig strand C' 70..73 CDD:409353 0/11 (0%)
Ig strand D 78..83 CDD:409353 2/4 (50%)
Ig strand E 85..91 CDD:409353 2/9 (22%)
Ig strand F 103..110 CDD:409353 2/6 (33%)
Ig strand G 114..124 CDD:409353 0/9 (0%)
Ig 131..218 CDD:416386 8/86 (9%)
Ig strand B 146..150 CDD:409353 0/3 (0%)
Ig strand C 159..163 CDD:409353 0/3 (0%)
Ig strand E 183..187 CDD:409353 2/3 (67%)
Ig strand F 197..202 CDD:409353 0/4 (0%)
Ig strand G 211..214 CDD:409353 0/2 (0%)
Ig_3 230..302 CDD:404760 21/75 (28%)
Ig strand B 247..251 CDD:409353 1/3 (33%)
Ig strand C 260..264 CDD:409353 0/3 (0%)
Ig strand E 282..286 CDD:409353 2/4 (50%)
Ig strand F 296..301 CDD:409353 2/4 (50%)
I-set 322..407 CDD:400151 24/119 (20%)
Ig strand C 352..357 CDD:409353 1/16 (6%)
Ig strand C' 359..362 CDD:409353 1/2 (50%)
Ig strand D 367..371 CDD:409353 0/3 (0%)
Ig strand E 373..378 CDD:409353 2/6 (33%)
Ig strand F 387..394 CDD:409353 3/6 (50%)
Ig strand G 398..407 CDD:409353 1/15 (7%)
FN3 414..507 CDD:238020
FN3 512..605 CDD:238020
fn3 619..694 CDD:394996
FN3 721..809 CDD:238020
FN3 816..906 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 974..1018
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1078..1193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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