DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and Btnl2

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_446267.1	Gene:	Btnl2 / 309620	RGDID:	620731	Length:	513	Species:	Rattus norvegicus

Alignment Length:	487	Identity:	106/487 - (21%)
Similarity:	169/487 - (34%)	Gaps:	96/487 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 TAQEDSDFPRFAEPIANVTVSVGRDALMACVV---ENLKGYKVAWVRVDTQTILSIHHNVISQNS 127
            |.:...|| |...|...:..:||.|||:.|.:   ......:|.|.|.|..|.:.::.:......
  Rat    22 TMKHPDDF-RVVGPALPILANVGEDALLTCRLLPKRTTARMEVRWYRSDPDTPVMLYRDGAEVPG 85

  Fly   128 RISLTYNDHRSWY----------LHIKEVEETDRGWYMCQVNT-DPMRSRKGYLQVVV----PPI 177
            .....|.....|.          |.|::|:..|.|.|.|::.. |..|.....|||..    |.|
  Rat    86 LAMEGYRGRVEWMEDSTEEGSVALKIRQVQPGDDGQYWCRIQEGDYWREASVLLQVAALGSSPNI 150

  Fly   178 IVEGLTSNDMVVREGQNISLVCKARG-YPEPYVMWRREDGEEML-IGGEHVNVVDGELLHITKVS 240
            .|||...        :.:.|||.:|| :|||.|.|....||::: :...||...||
  Rat   151 HVEGPGE--------EGVQLVCTSRGWFPEPEVYWEGIRGEKLMSLSENHVYGEDG--------- 198

  Fly   241 RLHMAAYLCVASNGVPPSISKRVHLR---------VQFPPMLSI---------PNQLEGAYLGQD 287
             |.......|..|....:||..::.|         :..|..|..         |:|.....:|:.
  Rat   199 -LFSVEDTLVVRNDSVETISCFIYNRGLREPQEATIALPEKLQTELASSRVIGPSQAIPVRVGET 262

  Fly   288 VILEC----HTEAYPASINYWTTERGDMIISDTSRAGDKYETTSTVSGYTKY---------MKLK 339
            :.|.|    .|:|....:.:.......::...|:.|.:..|..:...|.|..         :.|:
  Rat   263 IELTCQLSPQTDAQSLEVRWLRARYYPVVHVYTNGAHEAGEQMAEYRGRTSLVTDAIHEGKLTLQ 327

  Fly   340 IRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAIISEMSLLNRSYDGKRRHRNKFDSANA 404
            |.....:|.|.|||:........:..:.:..|...:|..|:...|    .||..:.|...|....
  Rat   328 IHNARTSDEGQYRCLFGKDGVYQEARVDVQVMAVGSTPQITREVL----KDGGTQLRCTSDGWFP 388

  Fly   405 LPDYGVEEWRDGAQGNNAGNNGDNNQTPVRNPPGAFHNSAGSLAQHNLLAKIMLGIKTQ-----S 464
            .|..   :|||          .|....|..:.  ||...:..|.|...|..:..|....     |
  Rat   389 RPHV---QWRD----------RDGRTLPSFSE--AFRQGSQELFQVETLLLVTNGSMVNVTCSIS 438

  Fly   465 FGIFKRLSSSLPLAAGQ-SFLWLSTLSLVSAP 495
            ..:.:..::..||:..: :.||: ||.::..|
  Rat   439 LPLGEEKTARFPLSDSRIALLWM-TLPVLVLP 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	23/105 (22%)
		IG_like	82..174	CDD:214653	25/105 (24%)
		IG_like	184..267	CDD:214653	22/93 (24%)
		IGc2	191..255	CDD:197706	19/65 (29%)
		IG_like	282..368	CDD:214653	17/98 (17%)
		Ig	288..367	CDD:143165	16/91 (18%)
Btnl2	NP_446267.1	IG_like	37..141	CDD:214653	23/103 (22%)
		Ig_MOG_like	43..142	CDD:143190	23/98 (23%)
		Ig	152..229	CDD:299845	25/94 (27%)
		IG_like	257..358	CDD:214653	17/100 (17%)
		Ig_MOG_like	260..358	CDD:143190	17/97 (18%)
		Ig	<379..444	CDD:299845	15/79 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000