DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and Pdcd1lg2

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001101052.2	Gene:	Pdcd1lg2 / 309304	RGDID:	1306403	Length:	268	Species:	Rattus norvegicus

Alignment Length:	163	Identity:	42/163 - (25%)
Similarity:	66/163 - (40%)	Gaps:	15/163 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 TVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYN----DHRSWYLHIK 144
            ||..|....:.|..:..:..::..:|...|   .:.::..||:.|.:|...    ...|:  ||.
  Rat    31 TVDFGSSVSLECDFDRRECTELEGIRASLQ---KVENDTSSQSQRATLLEELLPLGKASF--HIP 90

  Fly   145 EVEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARGYPEPYV 209
            .|:..|.|.|.|.|........| ||.|.|....|. :.:..:.|.....:.|:|:|||||...|
  Rat    91 SVQVRDSGQYRCLVICGAAWDYK-YLTVKVKASYVR-IDTGILEVPGTGEVQLICQARGYPLAEV 153

  Fly   210 MWRREDGEEMLIGGEHVNVVDGELLHITKVSRL 242
            .|:   ...:.....|:...:| |..:|.|.||
  Rat   154 SWQ---NVSVPANTSHIRTPEG-LYQVTSVLRL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	22/91 (24%)
		IG_like	82..174	CDD:214653	23/93 (25%)
		IG_like	184..267	CDD:214653	17/59 (29%)
		IGc2	191..255	CDD:197706	16/52 (31%)
		IG_like	282..368	CDD:214653
		Ig	288..367	CDD:143165
Pdcd1lg2	NP_001101052.2	IG_like	28..119	CDD:214653	23/93 (25%)
Pdcd1lg2	NP_001101052.2	Ig	137..193	CDD:299845	16/50 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000