DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-kappa and LRIT1

DIOPT Version :9

Sequence 1:NP_723828.1 Gene:DIP-kappa / 318958 FlyBaseID:FBgn0051814 Length:672 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:258 Identity:53/258 - (20%)
Similarity:87/258 - (33%) Gaps:66/258 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 PRFAEPIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYNDHRS 138
            |.....:|::...:|..||:.|....:.|.:::|.|.:.:.:....|..:|         :|..|
Human   254 PELHPGVASIRSLLGGTALLRCGATGVPGPEMSWRRANGRPLNGTVHQEVS---------SDGTS 309

  Fly   139 W-YLHIKEVEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKAR 202
            | .|.:..|...|.|.|:||.     ::..|..:.|:..|:.|..||.:   ..|          
Human   310 WTLLGLPAVSHLDSGDYICQA-----KNFLGASETVISLIVTEPPTSTE---HSG---------- 356

  Fly   203 GYPEPYVMWRREDGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLRV 267
               .|..:|.|..|     |||       ...:..|:...|:            |.|.|...|..
Human   357 ---SPGALWARTGG-----GGE-------AAAYNNKLVARHV------------PQIPKPAVLAT 394

  Fly   268 QFPPMLSIPNQLEGAYLGQDVILECHT-EAYPASINYWTTERGDMIISDTSRAGDKYETTSTV 329
            . |.:.|...:|...:...|.:.|... .|.|:...         ::......||.|.:.|.|
Human   395 G-PSVPSTKEELTLEHFQMDALGELSDGRAGPSEAR---------MVRSVKVVGDTYHSVSLV 447

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-kappaNP_723828.1 Ig 80..172 CDD:299845 21/92 (23%)
IG_like 82..174 CDD:214653 20/92 (22%)
IG_like 184..267 CDD:214653 15/82 (18%)
IGc2 191..255 CDD:197706 10/63 (16%)
IG_like 282..368 CDD:214653 9/49 (18%)
Ig 288..367 CDD:143165 8/43 (19%)
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 21/91 (23%)
IG_like 267..345 CDD:214653 21/91 (23%)
FN3 431..498 CDD:214495 5/17 (29%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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