DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and DIP-lambda

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001334747.1	Gene:	DIP-lambda / 26067049	FlyBaseID:	FBgn0267428	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	152/393 - (38%)
Similarity:	225/393 - (57%)	Gaps:	31/393 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TRRRFRLQAEFNVRQLAITIIATAAVTMLMTATPTLAEIPSKGKHTRLDTQQTAQEDSDFPRFAE 78
            |::..|::........:|..|...|:|  :|....:|.|..||:...:|           |:|..
  Fly     3 TKKTARIKMYNGTLACSIAFILIKAIT--ITKCHAVAHIHGKGESEEID-----------PQFLA 54

  Fly    79 PIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYNDHRSWYLHI 143
            .::|.||.:|||....|||:||..|:|||::.|::.||.||.:::|.|.|:|:|:|.|.:|.|||
  Fly    55 KLSNTTVPIGRDISFTCVVDNLGHYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNTWKLHI 119

  Fly   144 KEVEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSN--DMVVREGQNISLVCKARGYPE 206
            ..|:..|.|.||||||||||:|..|||.|||||.|:.....|  |.|.:||.:|||:|...|.|.
  Fly   120 SRVQINDSGSYMCQVNTDPMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPR 184

  Fly   207 PYVMWRREDGEEMLI---GGEHVNV--VDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLR 266
            |.|:||||.|:|:::   |.:....  |:||.|.:|.|.|..|..|.|:||||:|||:|||.::.
  Fly   185 PKVLWRREAGKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVY 249

  Fly   267 VQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDTSRAGDKYETTSTVSG 331
            |.|.|.:...:||.||.:.::|.|||..|.:|..:|.|....|::.:.:    |:||..:..|..
  Fly   250 VNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYRSEGNIKLHN----GNKYNISEEVIN 310

  Fly   332 -YTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTP---TTAIISEMSLLNRSYDGK 392
             ||.::.|.||.:..:|||||.|.:.|:||:::..|:|.|:..|   ||.....|....:|   :
  Fly   311 IYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTGKS---R 372

  Fly   393 RRH 395
            |:|
  Fly   373 RKH 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	48/91 (53%)
		IG_like	82..174	CDD:214653	49/91 (54%)
		IG_like	184..267	CDD:214653	40/89 (45%)
		IGc2	191..255	CDD:197706	30/68 (44%)
		IG_like	282..368	CDD:214653	29/86 (34%)
		Ig	288..367	CDD:143165	27/79 (34%)
DIP-lambda	NP_001334747.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11903
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8732
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	7	7.020