Protein Alignment DIP-kappa and NEGR1

DIOPT Version :9

• Sequence 1: NP_723828.1
• Gene: DIP-kappa / 318958
• FlyBaseID: FBgn0051814
• Length: 672
• Species: Drosophila melanogaster
• Sequence 2: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 91/327 - (27%)
• Similarity: 149/327 - (45%)
• Gaps: 58/327 - (17%)

  Fly    67 AQEDSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISL 131
            |.:..|||..|  :.|:.|..|..|::.|.:|: ...|.||  ::..:|:....:..|.:.|:|:
Human    34 AGQSVDFPWAA--VDNMMVRKGDTAVLRCYLED-GASKGAW--LNRSSIIFAGGDKWSVDPRVSI 93

  Fly   132 TYNDHRSWYLHIKEVEETDRGWYMCQVNTD-PMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNI 195
            :..:.|.:.|.|:.|:.||.|.|.|.|.|. ..|:.:.:|.|.|||.|.:  .||||.|.||.|:
Human    94 STLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYD--ISNDMTVNEGTNV 156

  Fly   196 SLVCKARGYPEPYVMWRREDGEEMLIGGEHVN-----VVDGELLHITKVSRLHMAAYLCVASNGV 255
            :|.|.|.|.|||.:.||            |::     ..:|:.|.|..::|.....|.|.|.|.|
Human   157 TLTCLATGKPEPSISWR------------HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDV 209

  Fly   256 PPSISKRVHLRVQFPPMLSIPNQLEGAYL--GQDVILECHTEAYPASINYW--------TTERGD 310
            .....::|.:.|.|.|.:   .:::...:  |:..::.|.....|.....|        ..::|.
Human   210 SFPDVRKVKVVVNFAPTI---QEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGI 271

  Fly   311 MIISDTSRAGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPT 375
            :|.:.::|      :..||:..|:           ..||.|.|||.|.||.|:.::.|:   .|:
Human   272 IIQNFSTR------SILTVTNVTQ-----------EHFGNYTCVAANKLGTTNASLPLN---PPS 316

  Fly   376 TA 377
            ||
Human   317 TA 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	26/92 (28%)
		IG_like	82..174	CDD:214653	27/92 (29%)
		IG_like	184..267	CDD:214653	28/87 (32%)
		IGc2	191..255	CDD:197706	21/68 (31%)
		IG_like	282..368	CDD:214653	20/95 (21%)
		Ig	288..367	CDD:143165	19/86 (22%)
NEGR1	NP_776169.2	IG	47..135	CDD:214652	26/90 (29%)
		IGc2	152..210	CDD:197706	21/69 (30%)
		Ig_3	225..301	CDD:372822	17/95 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143460
Domainoid	1	1.000	45	1.000	Domainoid score	I12195
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8497
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.750