DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-kappa and Ntm

DIOPT Version :9

Sequence 1:NP_723828.1 Gene:DIP-kappa / 318958 FlyBaseID:FBgn0051814 Length:672 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:318 Identity:104/318 - (32%)
Similarity:154/318 - (48%) Gaps:39/318 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 DSDFPRFAEPIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYN 134
            |:.||:..:   ||||..|..|.:.|.::| :..:|||  ::..|||...::....:.|:.|..|
Mouse    35 DATFPKAMD---NVTVRQGESATLRCTIDN-RVTRVAW--LNRSTILYAGNDKWCLDPRVVLLSN 93

  Fly   135 DHRSWYLHIKEVEETDRGWYMCQVNTD--PMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISL 197
            ....:.:.|:.|:..|.|.|.|.|.||  |..||. :|.|.|.|.|||  .|:|:.:.||.||||
Mouse    94 TQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVSPKIVE--ISSDISINEGNNISL 155

  Fly   198 VCKARGYPEPYVMWRREDGEEMLIGGEHVN------VVDGELLHITKVSRLHMAAYLCVASNGVP 256
            .|.|.|.|||.|.||            |::      |.:.|.|.|..::|.....|.|.|||.|.
Mouse   156 TCIATGRPEPTVTWR------------HISPKAVGFVSEDEYLEIQGITREQSGEYECSASNDVA 208

  Fly   257 PSISKRVHLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDTSRAGD 321
            ..:.:||.:.|.:||.:| ..:..|..:||...|:|...|.|::...|..:...::   ..:.|.
Mouse   209 APVVRRVKVTVNYPPYIS-EAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLV---EGKKGV 269

  Fly   322 KYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAII 379
            |.|....:|      ||....|..:|:|.|.|||.|.||.|:.:|.|.|:..||::.:
Mouse   270 KVENRPFLS------KLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEPTSSTL 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-kappaNP_723828.1 Ig 80..172 CDD:299845 30/93 (32%)
IG_like 82..174 CDD:214653 31/93 (33%)
IG_like 184..267 CDD:214653 31/88 (35%)
IGc2 191..255 CDD:197706 26/69 (38%)
IG_like 282..368 CDD:214653 25/85 (29%)
Ig 288..367 CDD:143165 22/78 (28%)
NtmNP_001344522.1 Ig 44..132 CDD:416386 30/91 (33%)
Ig strand A' 44..49 CDD:409353 4/4 (100%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 1/4 (25%)
FR2 64..70 CDD:409353 3/7 (43%)
Ig strand C 64..70 CDD:409353 3/7 (43%)
CDR2 71..83 CDD:409353 3/11 (27%)
Ig strand C' 72..76 CDD:409353 2/3 (67%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 9/33 (27%)
Ig strand D 87..94 CDD:409353 2/6 (33%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 2/3 (67%)
Ig strand G 123..132 CDD:409353 4/9 (44%)
FR4 125..132 CDD:409353 3/7 (43%)
Ig_3 136..205 CDD:404760 30/82 (37%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 5/8 (63%)
Ig strand F 197..205 CDD:409353 3/7 (43%)
Ig_3 222..299 CDD:404760 24/86 (28%)
putative Ig strand A 223..229 CDD:409353 2/6 (33%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 3/9 (33%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833626
Domainoid 1 1.000 49 1.000 Domainoid score I11709
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8732
orthoMCL 1 0.900 - - OOG6_104123
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3058
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
1110.680

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