DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and zig-2

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	55/217 - (25%)
Similarity:	82/217 - (37%)	Gaps:	51/217 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 PIIVEGLTSNDMVVREGQNISLVCKARGYPEPYVMWRREDGEEMLIGGEHV-NVVDGELLHITKV 239
            |::....|.||..|..|:...|.|.|.|.|.|.:.|....   |.|.||.. ||.:..|....:|
Worm    31 PLLKFTRTPNDSNVTFGEKFVLSCGANGAPLPSIYWELNG---MRIQGEETSNVYENILNDGKQV 92

  Fly   240 SRLHM---------------AAYLCVASNGVPPSISKRVHLRVQF--------------PPMLSI 275
            |...|               .||.|:..||    ::|..|:...|              .|.:|:
Worm    93 SNAAMVSSHYRIPCATARNSGAYKCIIDNG----LTKLEHVAKVFVGGNKTNCALNDNGAPFISM 153

  Fly   276 PNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDTSRAGDKYETTSTVSGYTKYMKLKI 340
            ............|.|.|.:|    :...|:..:|:.::::.   |::|:...  ||     .|.|
Worm   154 TVDFRLEISNNAVALSCRSE----TATEWSWHKGEQLLTND---GERYQMFP--SG-----DLII 204

  Fly   341 RAVGPNDFGTYRCVAKNSLGET 362
            |.:..:|.|.|.|.|:|..|||
Worm   205 RNISWSDMGEYNCTARNHFGET 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845
		IG_like	82..174	CDD:214653
		IG_like	184..267	CDD:214653	28/98 (29%)
		IGc2	191..255	CDD:197706	22/79 (28%)
		IG_like	282..368	CDD:214653	22/81 (27%)
		Ig	288..367	CDD:143165	22/75 (29%)
zig-2	NP_510069.1	I-set	34..134	CDD:254352	29/106 (27%)
		Ig	34..121	CDD:299845	25/89 (28%)
		Ig	<179..232	CDD:299845	17/58 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900