DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and Papln

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001192272.1	Gene:	Papln / 170721	MGIID:	2386139	Length:	1302	Species:	Mus musculus

Alignment Length:	171	Identity:	49/171 - (28%)
Similarity:	69/171 - (40%)	Gaps:	31/171 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 GQNISLVCKARGYPEPYVMWRREDGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVP 256
            ||.|.|.|:|.|:|.|.:.|:| || :::....|....||.|: |::|.......|.|||.||..
Mouse  1080 GQRIRLTCRAEGFPVPTIEWQR-DG-QLVSSPRHQVQPDGSLV-ISRVDVEDGGYYSCVAFNGQD 1141

  Fly   257 PSISKRVHLRV-------QFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIIS 314
            .. .:.|.|||       ..||.:::..       |....|.|....  .|:|...:..|..|.:
Mouse  1142 RD-QRWVQLRVLRELTITGLPPAVTVAE-------GDTARLLCVVAG--ESVNIRWSRNGLPIQA 1196

  Fly   315 DTSRAGDKYETTSTVSGYTKYMKLKIRAVGPNDFGTYRCVA 355
            |..|.....:.|           |.|..:.|.|.|:|.|.|
Mouse  1197 DGHRVHQSPDGT-----------LLIHNLRPRDEGSYTCSA 1226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845
		IG_like	82..174	CDD:214653
		IG_like	184..267	CDD:214653	27/74 (36%)
		IGc2	191..255	CDD:197706	24/62 (39%)
		IG_like	282..368	CDD:214653	18/74 (24%)
		Ig	288..367	CDD:143165	17/68 (25%)
Papln	NP_001192272.1	TSP1	30..81	CDD:214559
		ADAM_spacer1	184..299	CDD:368694
		TSP1	309..362	CDD:214559
		TSP1	389..447	CDD:214559
		TSP1	447..504	CDD:214559
		TSP1	511..562	CDD:214559
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	563..648
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	694..737
		Kunitz_BPTI	771..822	CDD:333766
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	822..924
		Papilin_u7	831..922	CDD:374683
		Ig	932..>995	CDD:386229
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1024..1064
		I-set	1070..1141	CDD:369462	25/63 (40%)
		Ig	1157..1241	CDD:386229	20/90 (22%)
		PLAC	1257..1289	CDD:370061
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900