DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and BTN3A1

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_008979.3	Gene:	BTN3A1 / 11119	HGNCID:	1138	Length:	513	Species:	Homo sapiens

Alignment Length:	160	Identity:	35/160 - (21%)
Similarity:	63/160 - (39%)	Gaps:	27/160 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 PIANVTVSVGRDALMAC---VVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYNDHRSWY 140
            |...:...||.||.:.|   ...:.:..::.||....:.:::::.:......|.|..|....|..
Human    36 PSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSIL 100

  Fly   141 ----------LHIKEVEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVV-----R 190
                      |.|..|..:|.|.|:|... |.....|..:::.|..:      .:|:.|     :
Human   101 RDGITAGKAALRIHNVTASDSGKYLCYFQ-DGDFYEKALVELKVAAL------GSDLHVDVKGYK 158

  Fly   191 EGQNISLVCKARG-YPEPYVMWRREDGEEM 219
            :| .|.|.|::.| ||:|.:.|....||.:
Human   159 DG-GIHLECRSTGWYPQPQIQWSNNKGENI 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	20/104 (19%)
		IG_like	82..174	CDD:214653	20/104 (19%)
		IG_like	184..267	CDD:214653	13/42 (31%)
		IGc2	191..255	CDD:197706	11/30 (37%)
		IG_like	282..368	CDD:214653
		Ig	288..367	CDD:143165
BTN3A1	NP_008979.3	IG_like	37..143	CDD:214653	20/106 (19%)
		Ig_MOG_like	45..144	CDD:143190	19/99 (19%)
		SPRY_PRY_BTN3	337..512	CDD:293992
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910