DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-kappa and Cd276

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_598744.1	Gene:	Cd276 / 102657	MGIID:	2183926	Length:	316	Species:	Mus musculus

Alignment Length:	221	Identity:	53/221 - (23%)
Similarity:	84/221 - (38%)	Gaps:	44/221 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 VTVSVGRDALMACVVENLKGYKVA-----WVRVDTQTILSIHHNVISQNSRISLTYNDHRSWY-- 140
            |...|..||.:.|......|:.:|     |...||:.::........|.|    .|::..:.:
Mouse    38 VVALVDTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGS----AYSNRTALFPD 98

  Fly   141 --------LHIKEVEETDRGWYMCQVNTDPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISL 197
                    |.::.|..||.|.|.|.|:.....|....|||..|..........:..:|.|..:::
Mouse    99 LLVQGNASLRLQRVRVTDEGSYTCFVSIQDFDSAAVSLQVAAPYSKPSMTLEPNKDLRPGNMVTI 163

  Fly   198 VCKA-RGYPEPYVMWRREDGEEMLIGGEHVNVVDGE------LLHITKVSRLHMAA---YLCVAS 252
            .|.: :||||..|.|:  ||:.:.:.|   ||...:      |..:..|.|:.:.|   |.|:..
Mouse   164 TCSSYQGYPEAEVFWK--DGQGVPLTG---NVTTSQMANERGLFDVHSVLRVVLGANGTYSCLVR 223

  Fly   253 NGVPPSISKRVHLRV-------QFPP 271
            |   |.:.:..|..|       .|||
Mouse   224 N---PVLQQDAHGSVTITGQPLTFPP 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	23/103 (22%)
		IG_like	82..174	CDD:214653	25/105 (24%)
		IG_like	184..267	CDD:214653	23/92 (25%)
		IGc2	191..255	CDD:197706	20/73 (27%)
		IG_like	282..368	CDD:214653
		Ig	288..367	CDD:143165
Cd276	NP_598744.1	IG_like	37..138	CDD:214653	23/103 (22%)
		Ig	44..139	CDD:299845	22/98 (22%)
		IgC	149..235	CDD:143166	23/93 (25%)
		IG_like	156..238	CDD:214653	24/89 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000