DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-kappa and iglon5

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	93/315 - (29%)
Similarity:	150/315 - (47%)	Gaps:	30/315 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 FAEPIANVTVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYNDHRSWY 140
            |..|..|.|||.|.:|.::|:::: |..:|||  ::...||....:..|.:||:.|..|....:.
Frog    29 FVPPADNYTVSQGDNATLSCLIDD-KVTRVAW--LNRSNILYAGKDKWSIDSRVQLLTNTKSEYS 90

  Fly   141 LHIKEVEETDRGWYMCQVNT-DPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARGY 204
            :.|..|:..|.|.|.|...| |...:.:.||.|.||..||.  .|:.:.|.||.|::|.|.|.|.
Frog    91 IVITHVDVADEGLYTCSFQTEDKPHTSQVYLIVQVPAKIVN--ISSSVTVNEGSNVNLQCLAVGK 153

  Fly   205 PEPYVMWRR-EDGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHLRVQ 268
            |||.:.|:: .:|...          :||||.||:::|.....|.||.||||....:|:|.:.|.
Frog   154 PEPTITWQQLSEGFSS----------EGELLEITEINRQQAGDYECVTSNGVSVPDTKKVQITVN 208

  Fly   269 FPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDTSRAGDKYETTSTVSGYT 333
            :||.::.....:.. :|:...|.|...|.|.:...|..:....:||.|.....|.|::.:|..::
Frog   209 YPPYITDVKNAQSP-VGRPATLRCKAMAVPPAEFEWYKDEKRRLISGTEGLSIKTESSWSVIVFS 272

  Fly   334 KYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKL----DEMPTPTTAIISEMSL 384
            .        |....:|.|.|:|.|.||..:.:::|    |.:....|.::|.:.|
Frog   273 N--------VTSRHYGNYTCLASNKLGSFNSSLRLLKPGDPLNQGATHMVSPLLL 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	28/92 (30%)
		IG_like	82..174	CDD:214653	29/92 (32%)
		IG_like	184..267	CDD:214653	30/83 (36%)
		IGc2	191..255	CDD:197706	24/64 (38%)
		IG_like	282..368	CDD:214653	20/85 (24%)
		Ig	288..367	CDD:143165	19/78 (24%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	29/94 (31%)
		IG_like	35..123	CDD:214653	28/90 (31%)
		Ig	126..207	CDD:299845	33/92 (36%)
		I-set	128..207	CDD:254352	32/90 (36%)
		I-set	210..299	CDD:254352	22/97 (23%)
		Ig	227..298	CDD:143165	19/78 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920