DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and lsamp

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	XP_031751462.1	Gene:	lsamp / 100124984	XenbaseID:	XB-GENE-5759171	Length:	368	Species:	Xenopus tropicalis

Alignment Length:	406	Identity:	113/406 - (27%)
Similarity:	171/406 - (42%)	Gaps:	78/406 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RLQAEFNVRQLAITIIATAAVTMLMTATPTLAEIPSKGKHTRLDTQQTAQEDSDFPRFAEPIANV 83
            |.||:.|  ||.:.::  ..:.:|.|..|.                    ...||.|..:   |:
Frog     4 RSQADRN--QLPLLLL--RLLCLLPTGLPV--------------------RSGDFNRSTD---NI 41

  Fly    84 TVSVGRDALMACVVENLKGYKVAWVRVDTQTILSIHHNVISQNSRISLTYNDHRSWYLHIKEVEE 148
            ||..|..|::.|.||: :..:|||  ::...|:....:..|.:.|:.|.......:.|.|::|:.
Frog    42 TVRQGDTAILRCFVED-RSSRVAW--LNRSGIIFAGDDKWSLDPRVELEKRSLLEYSLRIQKVDV 103

  Fly   149 TDRGWYMCQVNT-DPMRSRKGYLQVVVPPIIVEGLTSNDMVVREGQNISLVCKARGYPEPYVMWR 212
            :|.|.|.|.|.| ...::.:.||.|.|||.|..  .|.|:.|.||.|::|:|.|.|.|||.:.||
Frog   104 SDEGPYTCSVQTKQHTKTTQVYLIVQVPPKISN--ISADITVNEGSNVTLMCIAYGRPEPMITWR 166

  Fly   213 -----------RE-DGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRVHL 265
                       |: :|||             |.|.|..::|.....|.|.|:|.|..:..|:|.:
Frog   167 HLTPTAGTSPARDFEGEE-------------EFLEIQGITREQSGRYECKAANEVASADVKQVRV 218

  Fly   266 RVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINYWTTERGDMIISDT------SRAGDKYE 324
            .|.:||:::.....| |..|:..||.|...|.||....|..:       ||      |..|.:..
Frog   219 TVNYPPIITESKSNE-ATTGKQAILRCEASAVPAPDFEWYKD-------DTRSRRINSAQGLEIR 275

  Fly   325 TTSTVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDGNIKLDEMPTPTTAIISEMSLLNRSY 389
            .|.:.|      .|.:..|....:|.|.|||.|.||.|:.::.|.:..:||..:.:.....|..|
Frog   276 NTGSRS------VLMVANVTEEHYGNYTCVAANKLGITNTSLYLYKRVSPTKPMSASERGSNVHY 334

  Fly   390 DGKRRHRNKFDSANAL 405
            ..|.......|||.:|
Frog   335 QYKVGPGTPIDSATSL 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	26/92 (28%)
		IG_like	82..174	CDD:214653	27/92 (29%)
		IG_like	184..267	CDD:214653	30/94 (32%)
		IGc2	191..255	CDD:197706	24/75 (32%)
		IG_like	282..368	CDD:214653	26/91 (29%)
		Ig	288..367	CDD:143165	24/84 (29%)
lsamp	XP_031751462.1	Ig	38..128	CDD:416386	26/95 (27%)
		FR1	38..54	CDD:409353	5/18 (28%)
		Ig strand A'	39..45	CDD:409353	3/8 (38%)
		Ig strand B	47..55	CDD:409353	2/7 (29%)
		CDR1	55..59	CDD:409353	2/4 (50%)
		FR2	60..67	CDD:409353	3/8 (38%)
		Ig strand C	60..66	CDD:409353	3/7 (43%)
		CDR2	68..78	CDD:409353	1/9 (11%)
		Ig strand C'	70..73	CDD:409353	1/2 (50%)
		Ig strand C'	75..78	CDD:409353	0/2 (0%)
		FR3	79..114	CDD:409353	10/34 (29%)
		Ig strand D	83..90	CDD:409353	2/6 (33%)
		Ig strand E	93..99	CDD:409353	1/5 (20%)
		Ig strand F	106..114	CDD:409353	3/7 (43%)
		CDR3	115..119	CDD:409353	1/3 (33%)
		Ig strand G	119..128	CDD:409353	2/8 (25%)
		FR4	121..128	CDD:409353	2/6 (33%)
		Ig_3	131..206	CDD:404760	29/89 (33%)
		Ig strand A'	138..143	CDD:409353	2/4 (50%)
		Ig strand B	149..156	CDD:409353	2/6 (33%)
		Ig strand C	162..167	CDD:409353	1/4 (25%)
		Ig strand C'	173..175	CDD:409353	0/1 (0%)
		Ig strand E	185..191	CDD:409353	3/5 (60%)
		Ig strand F	198..205	CDD:409353	2/6 (33%)
		Ig strand G	212..220	CDD:409353	2/7 (29%)
		Ig_3	223..302	CDD:404760	25/92 (27%)
		putative Ig strand A	224..230	CDD:409353	1/5 (20%)
		Ig strand B	240..244	CDD:409353	2/3 (67%)
		Ig strand C	253..257	CDD:409353	0/3 (0%)
		Ig strand E	281..285	CDD:409353	2/9 (22%)
		Ig strand F	295..300	CDD:409353	2/4 (50%)
		Ig strand G	308..311	CDD:409353	0/2 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010