DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-kappa and igsf9

DIOPT Version :9

Sequence 1:	NP_723828.1	Gene:	DIP-kappa / 318958	FlyBaseID:	FBgn0051814	Length:	672	Species:	Drosophila melanogaster
Sequence 2:	NP_001090640.1	Gene:	igsf9 / 100036605	XenbaseID:	XB-GENE-989817	Length:	1423	Species:	Xenopus tropicalis

Alignment Length:	409	Identity:	101/409 - (24%)
Similarity:	153/409 - (37%)	Gaps:	81/409 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 VGRDALMACVVENLKG-----YKVAWVRVDTQTILSIHHNVISQNSRISLTY----NDHRSWYLH 142
            ||...::.|.:.:...     |.:.|||......:.|...:.|  .|:...|    .......||
Frog    32 VGESTVLGCSLLHQDAGRPPLYVIEWVRFGFMLPIFIKFGLYS--PRVDPQYLGRTRIEEGASLH 94

  Fly   143 IKEVEETDRGWYMCQV--------NTDPMRSRKGYLQVVVPPIIVEGLTSNDMV-VREGQNISLV 198
            |:.:...|:|||.|:|        ..|.......:|.|..||...|  |....| ||.|..::|.
Frog    95 IESLRSEDQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSPPSFRE--TPPTYVEVRVGDTLTLT 157

  Fly   199 CKARGYPEPYVMWRREDGEEMLIGGEHVNVVDGELLHITKVSRLHMAAYLCVASNGVPPSISKRV 263
            |.|.|.|:|.|.|:| || ..|..|:.|...:|. |.|..|.|.:...|.|.|.:. ...::...
Frog   158 CVAYGNPQPVVTWKR-DG-VTLESGDKVQASNGS-LSIVGVERGNAGVYTCHAFSD-EGEVTHTS 218

  Fly   264 HLRVQFPPMLSIPNQLEGAYLGQDVILECHTEAYPASINY-WTTERGDMIISDTSRAGDKYETTS 327
            .:.||.||::.:|.:.....:.||..|.|..|||||::.| |.....::.:.:..:.    ....
Frog   219 RVLVQGPPIIVVPPENTTVNVSQDAFLTCQAEAYPANLTYTWFQGSNNVFLLNRLQP----RVRI 279

  Fly   328 TVSGYTKYMKLKIRAVGPNDFGTYRCVAKNSLGETDG---------NIKLDEMPTPTTAIIS--- 380
            .|.|     ...|:.|.|.|.|.|.|:..|.:.::..         ...:..||..|...|.
Frog   280 LVDG-----SFLIQRVTPEDAGKYTCIPSNGMWKSPSASAYLTVLHPAYVTSMPAETYLPIGMRG 339

  Fly   381 ----------EMSLLNRSYDGKRRHRNKFDSANALPDYGVEE--------WRDGAQG-------N 420
                      .:.|:|.:.||.....:|:      |.:.|:|        ..|.|.|       |
Frog   340 VIKCPVRANPPLLLVNWTKDGHALELDKY------PGWYVDEDGSLVIATGNDDALGIYTCTPYN 398

  Fly   421 NAGNNGDNNQTPV--RNPP 437
            :.|..|.:..|.|  :.||
Frog   399 SYGTGGVSLPTEVILKEPP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-kappa	NP_723828.1	Ig	80..172	CDD:299845	22/101 (22%)
		IG_like	82..174	CDD:214653	23/103 (22%)
		IG_like	184..267	CDD:214653	26/83 (31%)
		IGc2	191..255	CDD:197706	23/63 (37%)
		IG_like	282..368	CDD:214653	21/95 (22%)
		Ig	288..367	CDD:143165	19/88 (22%)
igsf9	NP_001090640.1	Ig	25..132	CDD:299845	22/101 (22%)
		IG_like	25..110	CDD:214653	19/79 (24%)
		I-set	136..222	CDD:254352	29/91 (32%)
		IGc2	151..212	CDD:197706	23/64 (36%)
		Ig_2	226..318	CDD:290606	23/100 (23%)
		I-set	226..318	CDD:254352	23/100 (23%)
		IG_like	328..407	CDD:214653	17/84 (20%)
		Ig	340..402	CDD:299845	12/67 (18%)
		IG_like	431..502	CDD:214653
		Ig	439..502	CDD:299845
		FN3	507..601	CDD:238020
		FN3	624..714	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100