DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31810 and Hsd17b12

DIOPT Version :9

Sequence 1:NP_724023.1 Gene:CG31810 / 318955 FlyBaseID:FBgn0051810 Length:324 Species:Drosophila melanogaster
Sequence 2:NP_114455.2 Gene:Hsd17b12 / 84013 RGDID:708367 Length:312 Species:Rattus norvegicus


Alignment Length:320 Identity:117/320 - (36%)
Similarity:188/320 - (58%) Gaps:29/320 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 IYIVGSLSIVAYLYENLKSLFSIIKSVV------EPFFRPNLPKTLAEKFGNWAVVTGATDGIGK 70
            :|.||: |.:|||  .|::.:|:.::..      :.|..|.|        |.||||||.||||||
  Rat    11 LYWVGA-STIAYL--TLRASYSLFRAFQVWCVGNQAFVGPRL--------GEWAVVTGGTDGIGK 64

  Fly    71 EYARELARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKGREVYAHIEKELNGIEVG 135
            .||.|||::|:.:||:||.::||..|:|.|..::||:.:.|..||:.. ::|..|:..|:|:|:|
  Rat    65 SYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKFNVETRTIAVDFSLD-DIYDKIKTGLSGLEIG 128

  Fly   136 ILVNNVGTIHD-PESLDKVS--EDMLWDLLTVNVGSVTMLTRKILPQMISRRKGAIVNLGSSSEL 197
            :||||||..:: ||...::.  ::.:..|:.:||.|:..:||.:||.|:.|.||.|:|:.|:|.:
  Rat   129 VLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSICKVTRLVLPGMVERSKGVILNISSASGM 193

  Fly   198 QPHPNLTAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQGGLLFPNAYS 262
            .|.|.||.|:|||.||..|::.|..|.....|.||.|:|.||||.:    .|:|:..|..|:|.:
  Rat   194 LPVPLLTVYSATKAFVDFFSQCLHEEYKSKGIFVQSVLPFFVATKL----AKIRKPTLDKPSAET 254

  Fly   263 YARSAVFTLGKTSETNGFWVHGLQYAFMKLAPMDI--RTYFGYQLFKRMRIEAMEHRLKN 320
            :.:||:.|:|..:.|.|:.:|.:..:...:.|..|  :|..|:.  |.:|...::...||
  Rat   255 FVKSAIKTVGLQTRTTGYVIHAIMGSINSILPRWIYFKTIMGFN--KSLRNRYLKKTKKN 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31810NP_724023.1 PLN02780 12..310 CDD:166421 114/308 (37%)
17beta-HSD1_like_SDR_c 56..297 CDD:187614 98/243 (40%)
Hsd17b12NP_114455.2 17beta-HSD1_like_SDR_c 50..289 CDD:187614 98/243 (40%)
Di-lysine motif. /evidence=ECO:0000250 308..312 0/3 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53762
OrthoDB 1 1.010 - - D584062at33208
OrthoFinder 1 1.000 - - FOG0000465
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100431
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.830

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