DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31810 and hsd17b12

DIOPT Version :9

Sequence 1:	NP_724023.1	Gene:	CG31810 / 318955	FlyBaseID:	FBgn0051810	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001017234.1	Gene:	hsd17b12 / 549988	XenbaseID:	XB-GENE-945229	Length:	320	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	112/307 - (36%)
Similarity:	175/307 - (57%)	Gaps:	30/307 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LSIVAYLYENLKSLFSIIKSV----------VEPFFRPNLPKTLAEKFGNWAVVTGATDGIGKEY 72
            |.:||.::..|::.:.::...          |.|            :.|.|||||||||||||.|
Frog    20 LGVVAAVWWGLRAAWCLLDGARVWVLGSGAQVGP------------RIGKWAVVTGATDGIGKAY 72

  Fly    73 ARELARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKGREVYAHIEKELNGIEVGIL 137
            |.|||::|:|:||:||..|||..|..:|..::.|:.|.|.|||.|..|:|..||..|..:|:|:|
Frog    73 AEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTEIYGRIESGLRDLEIGVL 137

  Fly   138 VNNVGTIHD-PESLDKVS--EDMLWDLLTVNVGSVTMLTRKILPQMISRRKGAIVNLGSSSELQP 199
            |||||..:: ||...::.  |:.|..::.:|:.||..:||.:||.|:.|.:|.|:|:.|:|.:.|
Frog   138 VNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGMLGRGRGVILNISSASGMYP 202

  Fly   200 HPNLTAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQGGLLFPNAYSYA 264
            .|.||.|:|||.||..|::||:.|.....:.||.|:|.:|||.:    .|:|:.....|:..:|.
Frog   203 VPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL----AKIRKPTWDKPSPETYV 263

  Fly   265 RSAVFTLGKTSETNGFWVHGLQ-YAFMKLAPMDIRTYFGYQLFKRMR 310
            :||:.|:|..::|||:..|.:. :....|.|:......|.::.|.:|
Frog   264 QSALNTVGLQTQTNGYLPHAIMGWISTSLVPVSTAISLGMKMNKGLR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31810	NP_724023.1	PLN02780	12..310	CDD:166421	111/305 (36%)
CG31810	NP_724023.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	103/244 (42%)
hsd17b12	NP_001017234.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	103/244 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930