DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31810 and hsdl1

DIOPT Version :9

Sequence 1:	NP_724023.1	Gene:	CG31810 / 318955	FlyBaseID:	FBgn0051810	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001008607.1	Gene:	hsdl1 / 494064	ZFINID:	ZDB-GENE-041212-31	Length:	319	Species:	Danio rerio

Alignment Length:	285	Identity:	87/285 - (30%)
Similarity:	156/285 - (54%)	Gaps:	7/285 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VGSLSIVAYLYENLKSLFSI--IKSVVEPFFRPNL--PKTLAEKFGNWAVVTGATDGIGKEYARE 75
            |.:|::|...|...|::..:  ..|::..:|.|.|  .:.|::::|.||::.||::.|.|.||.|
Zfish    22 VETLALVGACYMASKTVIFMRDCYSLIRLYFVPRLVRHRDLSQQYGQWAIICGASEAIAKAYAEE 86

  Fly    76 LARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKGREVYAHIEKELNGIEVGILVNN 140
            |||.|:.::|:|:....:......|.:.|.|:...|.|||.:|......|:..::..::|.:||:
Zfish    87 LARHGICVILISKDLSSVSDTARLISNNYGVEAICIEADFNQGPSACKPIKDAISSKDIGFIVNS 151

  Fly   141 V-GTIHDPESLDKVSEDMLWDLLTVNVGSVTMLTRKILPQMISRRKGAIVNLGSSSELQPHPNLT 204
            . ||:...::..::||.:||..:..|:.:.|::||..||.|:.|.:||:||:.|.....|.|...
Zfish   152 FDGTLEISQNFLELSESVLWGTIDRNIAATTLVTRLALPAMMERGRGAVVNISSGHCFHPIPRKA 216

  Fly   205 AYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQGGLLFPNAYSYARSAVF 269
            |::|:..|:.:|::.|:||..:..:.||.::|..||:.....|  ......|.|:...||..|:.
Zfish   217 AFSASTAFLDNFSRSLQYEYGDQGVFVQSLLPFRVASQRPEGS--APPASWLVPSPQVYASHALS 279

  Fly   270 TLGKTSETNGFWVHGLQYAFMKLAP 294
            |||.:..|.|:|.|.:|...:|:.|
Zfish   280 TLGISHRTTGYWPHSMQLGLVKMMP 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31810	NP_724023.1	PLN02780	12..310	CDD:166421	87/285 (31%)
CG31810	NP_724023.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	77/240 (32%)
hsdl1	NP_001008607.1	Required for mitochondria translocation. /evidence=ECO:0000250	2..82		16/59 (27%)
		17beta-HSD1_like_SDR_c	67..307	CDD:187614	77/240 (32%)
		adh_short	68..248	CDD:278532	57/179 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574573
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H100660
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3003
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.720