DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31810 and XB5863530

DIOPT Version :9

Sequence 1:	NP_724023.1	Gene:	CG31810 / 318955	FlyBaseID:	FBgn0051810	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_002941866.3	Gene:	XB5863530 / 100497556	XenbaseID:	XB-GENE-5863531	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	300	Identity:	111/300 - (37%)
Similarity:	170/300 - (56%)	Gaps:	18/300 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALILQ--VISTGIYIVGSLSI--VAYLYENLKSLFSIIKSVVEPFFRPNLPKTLAEKFGNWAVV 61
            |..:|:  .:|.|..::|.:::  || :.:..:.|.......|..:::|||     .::|.||||
Frog    25 MVSVLEEGCLSRGFALIGLITVGYVA-ITQGWRILCGFRAHFVSHWWKPNL-----RQYGTWAVV 83

  Fly    62 TGATDGIGKEYARELARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKGREVYAHIE 126
            |||||||||.||.||||:|.::||:||..|||..|...|..:...|.|.|.||:.....:|..||
Frog    84 TGATDGIGKSYAEELARRGFDIVLISRSPEKLQRVAEGIEQKSGRKTKIIQADYTGDVGIYTPIE 148

  Fly   127 KELNGIEVGILVNNVGTIHDPES---LDKVS-EDMLWDLLTVNVGSVTMLTRKILPQMISRRKGA 187
            :.|.|:::|:||||||..:..|.   ||..: ::.|.:::..|:.||..:||.:||.|:.::||.
Frog   149 EGLKGLDIGVLVNNVGMAYSNEPVRFLDVPNVKERLTNVINCNIVSVLQMTRIVLPGMLKKKKGL 213

  Fly   188 IVNLGSSSELQPHPNLTAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQ 252
            |:|:.|.:...|.|.:..|::||.||.:|::.|..|.:...|.||.|||..|:||| ::..|
Frog   214 IINISSEAGSHPFPMVAVYSSTKVFVDYFSRCLHTEYSPQGITVQSVMPLLVSTNM-TFGIK--- 274

  Fly   253 GGLLFPNAYSYARSAVFTLGKTSETNGFWVHGLQYAFMKL 292
            ..:....:.||...|:.|:|.|:.|||...|.||..|..|
Frog   275 SNIFVKTSDSYVYDALNTVGSTTRTNGCLSHALQSYFFHL 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31810	NP_724023.1	PLN02780	12..310	CDD:166421	106/286 (37%)
CG31810	NP_724023.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	98/240 (41%)
XB5863530	XP_002941866.3	17beta-HSD1_like_SDR_c	78..315	CDD:187614	98/240 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930