Protein Alignment CG31809 and HSDL1

DIOPT Version :9

• Sequence 1: NP_001097168.1
• Gene: CG31809 / 318954
• FlyBaseID: FBgn0051809
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_113651.4
• Gene: HSDL1 / 83693
• HGNCID: 16475
• Length: 330
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 122/303 - (40%)
• Similarity: 185/303 - (61%)
• Gaps: 5/303 - (1%)

  Fly     9 SLSIAAFLYENLKSLFSI--IKSVVEPFFRPNLPK--TLAEKFGNWAVVTGATDGIGKEYARELA 69
            :|::....|...||:..|  ..|::...|.|.|..  .|.:::|.||||:||||||||.||.|||
Human    24 ALALVGAWYTARKSITVICDFYSLIRLHFIPRLGSRADLIKQYGRWAVVSGATDGIGKAYAEELA 88

  Fly    70 RQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKGREVYAHIEKELNGIEVGILVNNVG 134
            .:|||::|:||.||||..|..:|...|.|:...|||||:.|||:|..|.:.|...:|||||||||
Human    89 SRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKDVGILVNNVG 153

  Fly   135 TIHD-PESLDKVSEDMLWDLLTVNVGSVTMLTRKILPQMISRRKGAIVNLGSSSELQPHPNLTAY 198
            ..:. |:...::|||.|||::.||:.:.:::...:||.|:.|:|||||.:.|.|..:|.|.|.|:
Human   154 VFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAF 218

  Fly   199 AATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQGGLLFPNAYSYARSAVFTL 263
            :|:|.::.||::.|:||.|...|.||.::|.:|||:|.:.|:.:.:...|.|:...||..||.||
Human   219 SASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTL 283

  Fly   264 GKTSETNGFWVHGLQYALMKLFPMEIRTYFVYQLFKRMRIEAM 306
            |.:..|.|:|.|.:|:...:..|..:..:....|.:.:|.||:
Human   284 GISKRTTGYWSHSIQFLFAQYMPEWLWVWGANILNRSLRKEAL 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31809	NP_001097168.1	17beta-HSD1_like_SDR_c	48..286	CDD:187614	107/238 (45%)
		DltE	50..302	CDD:223377	108/252 (43%)
HSDL1	NP_113651.4	Required for mitochondria translocation	2..82		22/57 (39%)
		17beta-HSD1_like_SDR_c	67..309	CDD:187614	108/241 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141585
Domainoid	1	1.000	189	1.000	Domainoid score	I3291
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H100660
Inparanoid	1	1.050	230	1.000	Inparanoid score	I3445
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	1	1.000	-	-		otm40861
orthoMCL	1	0.900	-	-		OOG6_100431
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3003
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.670