Protein Alignment CG31809 and Hsd17b12

DIOPT Version :9

• Sequence 1: NP_001097168.1
• Gene: CG31809 / 318954
• FlyBaseID: FBgn0051809
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_062631.1
• Gene: Hsd17b12 / 56348
• MGIID: 1926967
• Length: 312
• Species: Mus musculus
• Alignment Length: 320
• Identity: 116/320 - (36%)
• Similarity: 185/320 - (57%)
• Gaps: 25/320 - (7%)

  Fly     2 GLIYIVGSLSIAAFLYENLKSLFSIIKSVV------EPFFRPNLPKTLAEKFGNWAVVTGATDGI 60
            |.:|.||:.:||   |..|::.:|:.::..      |....|.|        |.||||||.||||
Mouse     9 GFLYWVGASTIA---YLALRASYSLFRAFQVWCVGNEALVGPRL--------GEWAVVTGGTDGI 62

  Fly    61 GKEYARELARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKGREVYAHIEKELNGIE 125
            ||.||.|||::|:.:||:||.::||..|:|.|..::||:.:.|..||:.. ::|..|:..|:|:|
Mouse    63 GKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLD-DIYDKIKTGLSGLE 126

  Fly   126 VGILVNNVGTIHD-PESLDKVS--EDMLWDLLTVNVGSVTMLTRKILPQMISRRKGAIVNLGSSS 187
            :|:||||||..:: ||...::.  ::.:..|:.:||.||..:||.:||.|:.|.||.|:|:.|:|
Mouse   127 IGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSAS 191

  Fly   188 ELQPHPNLTAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQGGLLFPNA 252
            .:.|.|.||.|:|||.||..|::.|..|.....|.||.|||..|||.:    .|:::..|..|:|
Mouse   192 GMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKL----AKIQKPTLDKPSA 252

  Fly   253 YSYARSAVFTLGKTSETNGFWVHGLQYALMKLFPMEIRTYFVYQLFKRMRIEAMEHRLKN 312
            .::.:||:.|:|..:.|.|:.:|.|..::..:.|..:....:....|.:|...::.|.||
Mouse   253 ETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKIIMGFSKSLRNRYLKKRKKN 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31809	NP_001097168.1	17beta-HSD1_like_SDR_c	48..286	CDD:187614	98/240 (41%)
		DltE	50..302	CDD:223377	99/254 (39%)
Hsd17b12	NP_062631.1	NADB_Rossmann	<4..>83	CDD:304358	34/84 (40%)
		DltE	46..305	CDD:223377	103/271 (38%)
		17beta-HSD1_like_SDR_c	50..288	CDD:187614	99/242 (41%)
		Di-lysine motif. /evidence=ECO:0000250	308..312		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.803099	Normalized mean entropy	S1433
OMA	1	1.010	-	-		QHG53762
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100431
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.670