DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31809 and hsd17b12

DIOPT Version :9

Sequence 1:	NP_001097168.1	Gene:	CG31809 / 318954	FlyBaseID:	FBgn0051809	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001017234.1	Gene:	hsd17b12 / 549988	XenbaseID:	XB-GENE-945229	Length:	320	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	101/235 - (42%)
Similarity:	151/235 - (64%)	Gaps:	7/235 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KFGNWAVVTGATDGIGKEYARELARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKG 110
            :.|.|||||||||||||.||.|||::|:|:||:||..|||..|..:|..::.|:.|.|.|||.|.
Frog    54 RIGKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKP 118

  Fly   111 REVYAHIEKELNGIEVGILVNNVGTIHD-PESLDKVS--EDMLWDLLTVNVGSVTMLTRKILPQM 172
            .|:|..||..|..:|:|:||||||..:: ||...::.  |:.|..::.:|:.||..:||.:||.|
Frog   119 TEIYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPGM 183

  Fly   173 ISRRKGAIVNLGSSSELQPHPNLTAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNS 237
            :.|.:|.|:|:.|:|.:.|.|.||.|:|||.||..|::||:.|.....:.||.|:|.:|||.:
Frog   184 LGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPFYVATKL-- 246

  Fly   238 YSDKVRQGGLLFPNAYSYARSAVFTLGKTSETNGFWVHGL 277
              .|:|:.....|:..:|.:||:.|:|..::|||:..|.:
Frog   247 --AKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAI 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31809	NP_001097168.1	17beta-HSD1_like_SDR_c	48..286	CDD:187614	101/233 (43%)
CG31809	NP_001097168.1	DltE	50..302	CDD:223377	100/231 (43%)
hsd17b12	NP_001017234.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	101/233 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53762
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930