Protein Alignment CG31809 and HSD17B3

DIOPT Version :9

• Sequence 1: NP_001097168.1
• Gene: CG31809 / 318954
• FlyBaseID: FBgn0051809
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_000188.1
• Gene: HSD17B3 / 3293
• HGNCID: 5212
• Length: 310
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 97/253 - (38%)
• Similarity: 143/253 - (56%)
• Gaps: 14/253 - (5%)

  Fly    39 LPKTLAEKFGNWAVVTGATDGIGKEYARELARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWI 103
            |||:.....|.|||:|||.|||||.|:.|||::|||:||:||..|||.|:..||.......:|.|
Human    39 LPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKII 103

  Fly   104 VADFAKGREVYAHIEKELNGIEVGILVNNVGTIHDPESLDK---VSEDMLWDLLTVNVGSVTMLT 165
            .|||.|. ::|.||:::|.|:|:||||||||.:  |..|..   .:.|.:..|:..|:.||..:|
Human   104 QADFTKD-DIYEHIKEKLAGLEIGILVNNVGML--PNLLPSHFLNAPDEIQSLIHCNITSVVKMT 165

  Fly   166 RKILPQMISRRKGAIVNLGSSSELQPHPNLTAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAF 230
            :.||..|.||:||.|:|:.|...|.|.|..:.|:|:|.||..|:|.|:.|.....:.:|::.|..
Human   166 QLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYA 230

  Fly   231 VATNMNSYSDKVRQGGLLFPNAYSYARSAV--FTLGKTSETNGFWVHGLQYALMKLFP 286
            |:|.|..|.:.    .::...|..:.:.::  .|:|  .||.|...|.:....:.|.|
Human   231 VSTAMTKYLNT----NVITKTADEFVKESLNYVTIG--GETCGCLAHEILAGFLSLIP 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31809	NP_001097168.1	17beta-HSD1_like_SDR_c	48..286	CDD:187614	93/242 (38%)
		DltE	50..302	CDD:223377	93/242 (38%)
HSD17B3	NP_000188.1	17beta-HSD1_like_SDR_c	48..284	CDD:187614	94/244 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820