Protein Alignment CG31809 and Hsd17b3

DIOPT Version :10

• Sequence 1: NP_001097168.1
• Gene: CG31809 / 318954
• FlyBaseID: FBgn0051809
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_446459.1
• Gene: Hsd17b3 / 117182
• RGDID: 621805
• Length: 306
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 102/314 - (32%)
• Similarity: 165/314 - (52%)
• Gaps: 30/314 - (9%)

  Fly     3 LIYIVGSLSIAAFLYENLKSLFSIIKSVVEPFFRPNLPKTLAEKFGNWAVVTGATDGIGKEYARE 67
            |:.:|..:..:.:|:      .|..|:         ||.:.....|.|||:|||.|||||.|:.|
  Rat    14 LVCLVKCVRFSRYLF------LSFCKA---------LPGSFLRSMGQWAVITGAGDGIGKAYSFE 63

  Fly    68 LARQGLNLVLVSRKEEKLIAVTNEIGSQYNVKIKWIVADFAKGREVYAHIEKELNGIEVGILVNN 132
            |||.|||:||:||..|||..::.||......::|.:.|||.: .::|.|||::|.|:|:|:||||
  Rat    64 LARHGLNVVLISRTLEKLQVISEEIERTTGSRVKVVQADFTR-EDIYDHIEEQLKGLEIGVLVNN 127

  Fly   133 VGTIHD--PESLDKVSEDMLWDLLTVNVGSVTMLTRKILPQMISRRKGAIVNLGSSSELQPHPNL 195
            ||.:.:  |......|.:. ..::..|:.||..:|:.:|..|.|||:|.|:|:.|...::|.|..
  Rat   128 VGMLPNLLPSHFLSTSGES-QSVIHCNITSVVKMTQLVLKHMESRRRGLILNISSGVGVRPWPLY 191

  Fly   196 TAYAATKKFVTHFTKGLEYEVAEHNIHVQLVMPAFVATNMNSYSDKVRQGGLLFPNAYSYARSAV 260
            :.|:|:|.||..|:|.|..|..:..|.:|::.|..|:|.|..|.:..|    :...|..:.:.::
  Rat   192 SLYSASKAFVCTFSKALNVEYRDKGIIIQVLTPYSVSTPMTKYLNTSR----VTKTADEFVKESL 252

  Fly   261 --FTLGKTSETNGFWVHGLQYALMKLFPMEIRTYFVYQLFKRMRIEAMEHRLKN 312
              .|:|  :||.|...|.:...::.|.|..|   |.....:|..::.....||:
  Rat   253 KYVTIG--AETCGCLAHEILAIILNLIPSRI---FYSSTTQRFLLKQFSDYLKS 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31809	NP_001097168.1	17beta-HSD1_like_SDR_c	48..286	CDD:187614	89/241 (37%)
Hsd17b3	NP_446459.1	17beta-HSD1_like_SDR_c	44..281	CDD:187614	90/244 (37%)