DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31802 and CETN3

DIOPT Version :9

Sequence 1:	NP_724103.1	Gene:	CG31802 / 318949	FlyBaseID:	FBgn0051802	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_001284694.1	Gene:	CETN3 / 1070	HGNCID:	1868	Length:	191	Species:	Homo sapiens

Alignment Length:	159	Identity:	69/159 - (43%)
Similarity:	106/159 - (66%)	Gaps:	5/159 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SASISSRAKKSKKPKLPTFDLSLSQKVDIKKAFDLFDTQCTGFIETKELRVAIRALGFEPKKEDI 83
            |..:..:.|:.|:.     :||..||.:||.||:||||.....|:..||:||:|||||:.||.|:
Human     7 SELVVDKTKRKKRR-----ELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADV 66

  Fly    84 KRMMDEIDKDKTGRIAFNDFLYLMRLKMAEKDSNQDMMKAFSFFDDDRTGGISFLNLKRVAKELG 148
            .:::.:.|::.||:|.|.||..::...:.|:|.:::::|||..||||.:|.||..||:|||:|||
Human    67 LKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELG 131

  Fly   149 EQLTDEELQEMIDEANVSGDGEVSKEEFL 177
            |.::||||:.||:|.:..||||:.|...|
Human   132 ENMSDEELRAMIEEFDKDGDGEILKNILL 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31802	NP_724103.1	PTZ00183	38..185	CDD:185503	66/140 (47%)
		EFh	46..108	CDD:238008	28/61 (46%)
		EFh	119..181	CDD:238008	32/59 (54%)
CETN3	NP_001284694.1	PTZ00183	15..190	CDD:185503	68/151 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53747
OrthoDB	1	1.010	-	-		D512630at33208
OrthoFinder	1	1.000	-	-		FOG0000932
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X601
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.790