DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31787 and ERP4

DIOPT Version :9

Sequence 1:	NP_724105.1	Gene:	CG31787 / 318941	FlyBaseID:	FBgn0051787	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_014659.1	Gene:	ERP4 / 854181	SGDID:	S000005542	Length:	207	Species:	Saccharomyces cerevisiae

Alignment Length:	227	Identity:	57/227 - (25%)
Similarity:	107/227 - (47%)	Gaps:	38/227 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RVIWLLQLL----LLLDLKFSNAEPHNKQLTVFAEAGRQECFYQPIATTENI-KIDYQVIHGGLG 65
            ||..|:.:|    ||.....||..|....|..|.    :||.|..:::.::: .:.|||:.||..
Yeast     2 RVFTLIAILFSSSLLTHAFSSNYAPVGISLPAFT----KECLYYDLSSDKDVLVVSYQVLTGGNF 62

  Fly    66 ETHINFNLMDPSRRLLIAETKRQMGKHSIQANETGSYKFCFDNTISTFNQKIVSFTLEVAPADRE 130
            |  |:|::..|...:::.|.:::.....:::...|.|.||..|...| :.|.|..|||      :
Yeast    63 E--IDFDITAPDGSVIVTERQKKHSDFLLKSFGIGKYTFCLSNNYGT-SPKKVEITLE------K 118

  Fly   131 EREL---RDLRQEMLTDYHFDVAYTGIDSYVGKIHVNLMRSRQTQDFIRAIEARDRNVAESTYSM 192
            |:|:   .:.:::::.           ::.:.:|..||.:..:|.|::||.|.|:.....||.|
Yeast   119 EKEIVSSHESKEDIIA-----------NNAIEEIDRNLNKITKTMDYLRAREWRNMYTVSSTES- 171

  Fly   193 VNKWSWAQFLSM-IFVG--FLQVLMVRSIFNT 221
              :.:|...|.| :.||  .:|.|:::..|.:
Yeast   172 --RLTWLSLLIMGVMVGISIVQALIIQFFFTS 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31787	NP_724105.1	EMP24_GP25L	30..220	CDD:279450	47/196 (24%)
ERP4	NP_014659.1	EMP24_GP25L	29..199	CDD:395878	47/196 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346449
Domainoid	1	1.000	62	1.000	Domainoid score	I2479
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I1757
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103696
Panther	1	1.100	-	-	O	PTHR22811
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1790
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780