DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31787 and ERP2

DIOPT Version :9

Sequence 1:	NP_724105.1	Gene:	CG31787 / 318941	FlyBaseID:	FBgn0051787	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_009395.1	Gene:	ERP2 / 851226	SGDID:	S000000005	Length:	215	Species:	Saccharomyces cerevisiae

Alignment Length:	230	Identity:	62/230 - (26%)
Similarity:	108/230 - (46%)	Gaps:	32/230 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IARVIWLLQLLLLLDLKFSN---AEPHNKQLTVFAEAGRQECFYQPIAT-TENIKIDYQVIHGGL 64
            |...|.|....::|.|...|   |......:.:...|..:||.|..:.| .:::.:.|||:.||.
Yeast     2 IKSTIALPSFFIVLILALVNSVAASSSYAPVAISLPAFSKECLYYDMVTEDDSLAVGYQVLTGGN 66

  Fly    65 GETHINFNLMDPSRRLLIAETKRQMGKHSIQANETGSYKFCFDNTISTFNQKIVSFTLEVAPADR 129
            .|  |:|::..|...::.:|.:::.....:::...|.|.|||.|...|..:| |..|||
Yeast    67 FE--IDFDITAPDGSVITSEKQKKYSDFLLKSFGVGKYTFCFSNNYGTALKK-VEITLE------ 122

  Fly   130 EERELRDLRQEMLTDYH-FDVAYTGI--DSYVGKIHVNLMRSRQTQDFIRAIEARDRNVAESTYS 191
                    :::.|||.| .||....|  ::.|.:|..||.:..:|.:::||.|.|:.:...||.|
Yeast   123 --------KEKTLTDEHEADVNNDDIIANNAVEEIDRNLNKITKTLNYLRAREWRNMSTVNSTES 179

  Fly   192 MVNKWSWAQFLSMIFVGFL---QVLMVRSIFNTTG 223
               :.:|...|.:|.:..:   |||:::.:|  ||
Yeast   180 ---RLTWLSILIIIIIAVISIAQVLLIQFLF--TG 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31787	NP_724105.1	EMP24_GP25L	30..220	CDD:279450	52/196 (27%)
ERP2	NP_009395.1	EMP24_GP25L	34..183	CDD:395878	46/168 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346451
Domainoid	1	1.000	62	1.000	Domainoid score	I2479
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I1757
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103696
Panther	1	1.100	-	-	O	PTHR22811
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1790
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780