DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31787 and Tmed7

DIOPT Version :9

Sequence 1:	NP_724105.1	Gene:	CG31787 / 318941	FlyBaseID:	FBgn0051787	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_079974.1	Gene:	Tmed7 / 66676	MGIID:	1913926	Length:	224	Species:	Mus musculus

Alignment Length:	221	Identity:	67/221 - (30%)
Similarity:	97/221 - (43%)	Gaps:	27/221 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLQLLLLLDLKFSNAEPHNKQLTVFAEAGRQECFYQPIATTENIKIDYQVIHGGLGETHINFNLM 74
            ||.|||||.     |.....::|.......::|||:.|.......:::|||.|  |...::..|.
Mouse    21 LLALLLLLP-----APSGGSEITFELPDNAKQCFYEDITQGTKCTLEFQVITG--GHYDVDCRLE 78

  Fly    75 DPSRRLLIAETKRQMGKHSIQANETGSYKFCFDNTISTFNQKIVSFTLEVA---PADREERELRD 136
            ||..::|..|.|:|....:..|:..|:|||||.|..|||..|.|.|..:|.   |....|..:.
Mouse    79 DPDGKVLYKEMKKQYDSFTFTASRNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVS- 142

  Fly   137 LRQEMLTDYHFDVAYTGIDSYVGKIHVNLMRSRQTQDFIRAIEARDRNVAESTYSMVNKWSWAQF 201
                         |.|.::|....||..|......|...|..||:.|:.||...:.|..||..:.
Mouse   143 -------------ALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEA 194

  Fly   202 LSMIFVGFLQVLMVRSIFN---TTGT 224
            |.::.|...||.:::|.|:   ||.|
Mouse   195 LILLVVSVGQVFLLKSFFSDKRTTTT 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31787	NP_724105.1	EMP24_GP25L	30..220	CDD:279450	55/192 (29%)
Tmed7	NP_079974.1	EMP24_GP25L	36..213	CDD:307313	55/192 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1693
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1292519at2759
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103696
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1790
SonicParanoid	1	1.000	-	-		X1789
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.750