DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31784 and Ccdc96

DIOPT Version :9

Sequence 1:	NP_724035.2	Gene:	CG31784 / 318939	FlyBaseID:	FBgn0051784	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	XP_038948752.1	Gene:	Ccdc96 / 289716	RGDID:	1305153	Length:	642	Species:	Rattus norvegicus

Alignment Length:	567	Identity:	116/567 - (20%)
Similarity:	226/567 - (39%)	Gaps:	138/567 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 SILSEFETEKEFTVSDQESDVEDPEDKKQSERIRFLEIFGSLPDINNLSASESVESIQLIKEKEK 297
            |:.:|...|.|:|      .||.||..:.|      |:.|...:..:.:.|:..||:...|.|.:
  Rat   118 SLKAEASDEHEYT------PVEAPESPRDS------EVAGEAVEAASEAVSQEPESLPQTKPKTE 170

  Fly   298 VLPAVKNDRDQKEPDSFADL-----QVEDEYTENLDQKTHSLEISSES----------LIE---- 343
            ..|....|:|:.|.:..:|.     :.|||..:..::|....|.:.||          ::|
  Rat   171 AEPKEPEDKDEDEDEDESDEDEDEDEDEDEELDKSEKKKGKREKTKESRFRPSLPLTTIVEEAAA 235

  Fly   344 ----------------TDEEIYNDIVPEESQDNDISGHLLSIQIRSTILDASTSDLFNEIHMTNV 392
                            ..|||  :::..|.:......||..                .|......
  Rat   236 PAPRAAKEKAKGPQKRDSEEI--EVIGGEPRKKSTEEHLQP----------------GEEKEEGE 282

  Fly   393 AMVEQFLTGLINEVVKYDE-RTSVRLRRLLDKE---KMLEELYLLVID---YQ-YEMHRNQALER 449
            ..||:     :.:....|| ..|..:|:|.:::   :::|:.:.|:::   || |.::..|.:..
  Rat   283 EKVEK-----VEKEADADEFEWSADVRKLQEQQLRGELVEQYHSLLVERNRYQRYNVYLQQKIHE 342

  Fly   450 SVADYYVRRKEFSLVSE--DKQIDTINRE------RLMSALVELDN---------RLEQVQLTEK 497
            :     :|:|.....:|  ||..:..:.|      |.::.|.||..         |.|..:|.::
  Rat   343 T-----LRKKGLEAAAEPVDKGAEPESPEKEQAYLRYLAMLEELKKQEADDLEWYRHEVRELKQQ 402

  Fly   498 LSVKQVNTLIEKE-EEARALDAQIIAKF----------EAKVRETLCKEGLDRITIVVNDLLKKM 551
            ...||..  :||| :..:||..|::.:.          :|.:||      :::|..:.:...|:|
  Rat   403 CQEKQAK--VEKEWKRFQALKKQVVMQVMGSCRMRGGRQAALRE------VEQIQALEDKKEKEM 459

  Fly   552 NKTRDETSDVRKELLFVQHRLQALKNKSEKLENLGDGLRVLEYISNQARNNALRLKIKEKELELK 616
            :..|.|...:::.|:..:.|::|       .|:|.:||.::::...:..|.....|::|:..||.
  Rat   460 SAVRLENVQLKQSLVHFETRMKA-------QEDLAEGLLLIDFEQLKIENQTFNEKVEERNEELL 517

  Fly   617 RFRDRKTYDVHALAHLKNKKKINEELLNNMKSKLRTQQKLEKDLRARHYREMV-----KHEWVKK 676
            :.|.:.|.:|..:.|:|.|....:     |::..:..|..|.|.:....|:::     ..:.::.
  Rat   518 KLRTKVTSNVQIITHVKEKLSFID-----MENSCKKAQLSEVDAKVALGRDLLTKTKQARDSLRT 577

  Fly   677 KILKLKRAGCLMHYPDLLLDYDATV--NHLQSKRLVVRKLRHEHLRL 721
            ..:||.:...|:....||.|.:..|  ..|.::||...|..|..|.|
  Rat   578 DNVKLSQKCGLLGKESLLRDLEEKVEKTELLNRRLESLKRHHAGLAL 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31784	NP_724035.2	DUF4201	551..727	CDD:290581	40/178 (22%)
Ccdc96	XP_038948752.1	DUF4201	452..628	CDD:404711	41/185 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10377
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	64	1.000	Inparanoid score	I5269
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050