DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and f7

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	94/363 - (25%)
Similarity:	151/363 - (41%)	Gaps:	71/363 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QGQNAELN----QSCGASNEHQCVPRHMCKVKIEFRMAMTYRNLGCV------STAICCPKNLII 77
            :|::.|.|    ..|...| .||  .|.|...     :.|.|...|.      :..:.|
Frog   139 EGRHCETNLRDMLKCIYDN-GQC--EHFCHDN-----SSTSRQCSCAEGYKLGADGLSC------ 189

  Fly    78 KEPRLIINEPITDPQCGFVN-SKGVTFSFREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAP 141
                    ||..:..||.:. .|.|....|.....:..:.|.||...|:  ....::.||.||||
Frog   190 --------EPTVNYPCGKIPVLKNVNKRARIVGGDMCPKGECPWQALLM--YNEIFICGGTLIAP 244

  Fly   142 HVVITARQRTENMTASQLVVRAGEWDFSTK--TEQLPSVDVPIRSIVRHPGF--NLENGANNVAL 202
            :.||||....:.:..::|.|..||....|.  |||    :..:..|:.|..:  :..|..|::||
Frog   245 NWVITAAHCLKPLPENKLTVVLGEHRIGTPEGTEQ----ESKVSKIIMHEHYYGSKTNNDNDIAL 305

  Fly   203 VFLRRSLTSSRHINPICMPSAPKNFDFSRCI------FTGWGKNSFDDPSYMNVLKKISLPVVQR 261
            :.|...:..:.::.|:|:|.  |.|.....:      .:|||: ..:..:...:|:::.||.|:.
Frog   306 LKLTTPVNYTDYVVPLCLPE--KQFAVQELLSIRYSTVSGWGR-LLESGATPELLQRVQLPRVKT 367

  Fly   262 RTCEQQLRLYYGNDFELDNSLMCAGGEPG-KDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDC 325
            :.|.:|.::      .:..::.|||...| ||||:||.|.|.|...|:.   :.|.|||::|:.|
Frog   368 QDCIRQTQM------NISQNMFCAGYTDGSKDSCKGDSGGPHATQYKNT---HFLTGIVSWGLGC 423

  Fly   326 GLPGVPAVYTNVANVIEWITLTTVNMPLPEEREEVPYA 363
            .......|||.|:...|||         .|..:|.|.|
Frog   424 AKKEKYGVYTRVSRYTEWI---------KENMDEQPEA 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	68/241 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	68/241 (28%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011	1/4 (25%)
		FXa_inhibition	153..189	CDD:373209	9/43 (21%)
		Tryp_SPc	212..445	CDD:238113	70/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910