DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and tmprss4a

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_005157547.1	Gene:	tmprss4a / 777630	ZFINID:	ZDB-GENE-061103-631	Length:	458	Species:	Danio rerio

Alignment Length:	275	Identity:	74/275 - (26%)
Similarity:	124/275 - (45%)	Gaps:	52/275 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 VNSKGVTFSFR-EEDTGLA---------QEAEV---PWMVALLDARTSSYVAGGALIAPHVVITA 147
            |.|.|...|.. ..|.||:         ::|::   ||.|:|  ..:..:..||:|:.|:.|:||
Zfish   200 VCSTGTVISLSCSADCGLSRNQDRIVGGKDADIANWPWQVSL--QYSGQHTCGGSLVTPNWVVTA 262

  Fly   148 --------RQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVF 204
                    |:.....|    ||....:..||.:..       ::.|:.:..:.......::.::.
Zfish   263 AHCFNGDGRKALSRWT----VVSGITYLSSTPSSY-------VKEIIVNSNYKPAESDFDITMIK 316

  Fly   205 LRRSLTSSRHINPICMPSAPKNFDF---SRCIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQ 266
            |:..:|.|....|:|:|  |:|...   ...:.||||..:....|..::|:|..:.|:....|..
Zfish   317 LQSPITLSESRRPVCLP--PQNLGLKGGDGLVVTGWGHMAEKGGSLSSMLQKAQIQVIDSAQCSS 379

  Fly   267 QLRLYYGNDFELDNSLMCAG---GEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLP 328
            .  ..||:  .:...::|||   |  |.|:|:||.|.||. .:.|   |:.|.|:|::||.|..|
Zfish   380 P--TVYGS--SITPRMICAGVMAG--GVDACQGDSGGPLV-HLAD---RWVLVGVVSWGVGCARP 434

  Fly   329 GVPAVYTNVANVIEW 343
            |.|.|||||..:::|
Zfish   435 GFPGVYTNVDQMLDW 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	67/257 (26%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	67/257 (26%)
tmprss4a	XP_005157547.1	LDLa	74..105	CDD:238060
		SRCR_2	121..218	CDD:295335	6/17 (35%)
		Tryp_SPc	223..449	CDD:214473	66/250 (26%)
		Tryp_SPc	224..449	CDD:238113	66/249 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910