DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and st14b

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	358	Identity:	89/358 - (24%)
Similarity:	151/358 - (42%)	Gaps:	77/358 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VAGQVQAQGQNAELNQSCG-ASNEHQCV---------PRHMCKVKIEFRMAMTYRNLGCVS--TA 68
            ::.|.|..|.|     .|| .|:|.:|.         ..:.||            |..|:|  ..
Zfish   549 ISAQKQCNGYN-----DCGDGSDESRCAKSIAVHCSDSTYKCK------------NKQCISKLNP 596

  Fly    69 ICCPKNLIIKEPRLIINEPITDPQCG--------FVNSKGVTFSFREEDTGLAQEAEVPWMVALL 125
            :|      ..|...:......:.:||        .|..|.            :.|.|.||.|: |
Zfish   597 MC------DGETDCVDGSDEAECKCGKKPHKSSRIVGGKD------------SDEGEWPWQVS-L 642

  Fly   126 DARTSSYVAGGALIAPHVVITAR---QRTENMTASQLVVRAGEWD----FSTKTEQLPSVDVPIR 183
            ..:|..:|.|.::|:...::||.   |..:....||    |.:|:    ...:.|...|....:.
Zfish   643 HMKTQGHVCGASVISNSWLVTAAHCVQDNDQFRYSQ----ADQWEVYLGLHNQGETSKSTQRSVL 703

  Fly   184 SIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIF-TGWGKNSFDDPSY 247
            .|:.||.::..:..|::||:.|...:|.:::|.|||:|.....|...:.:: |||||......:.
Zfish   704 RIIPHPQYDHSSYDNDIALMELDSPVTLNQNIWPICLPDPTHYFPAGKSVWITGWGKLREGSDAV 768

  Fly   248 MNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGG-EPGKDSCEGDGGSPLACAIKDNPQ 311
            .:||:|..:.::....|.:.:      |..:...::|||. ..|.|:|:||.|.|:: :|:.|.:
Zfish   769 PSVLQKAEVRIINSTVCSKLM------DDGITPHMICAGVLSGGVDACQGDSGGPMS-SIEGNGR 826

  Fly   312 RYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            .: |||:|::|..||....|.|||.|.:...||
Zfish   827 MF-LAGVVSWGDGCGRRNRPGVYTRVTDYRSWI 858

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	67/239 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	67/239 (28%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060	8/25 (32%)
		LDLa	578..613	CDD:238060	7/52 (13%)
		Tryp_SPc	624..858	CDD:214473	69/258 (27%)
		Tryp_SPc	625..861	CDD:238113	71/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910