DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and st14a

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001035441.2	Gene:	st14a / 678603	ZFINID:	ZDB-GENE-030131-6496	Length:	834	Species:	Danio rerio

Alignment Length:	355	Identity:	91/355 - (25%)
Similarity:	152/355 - (42%)	Gaps:	69/355 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ELNQSCGA-----------SNEHQCVPRHMCKVKIEFRMAMTYRNLGCVSTAIC------CPKNL 75
            |||..|.|           |.:.:|..:..|....:        ..||..|..|      |..:.
Zfish   505 ELNCGCRADQFKCKNDKCISEKQKCDGKDDCNDGSD--------EEGCARTDSCLVSTFLCGNSK 561

  Fly    76 IIKEPRLIINEPITDPQ--CG----FVNSKGVTFSFRE------EDTGLAQEAEVPWMVALLDAR 128
            .|.:|     .|..|.|  ||    ..|....|.::::      :|   |.|.|.||.|: |..:
Zfish   562 CITKP-----NPECDGQDDCGDNSDESNCNCGTKAYKKSRIVGGQD---AFEGEFPWQVS-LHIK 617

  Fly   129 TSSYVAGGALIAPHVVITAR---QRTENMTASQLVVRAGEWD----FSTKTEQLPSVDVPIRSIV 186
            ..::|.||::|....::||.   |....:..||    .|.|:    ..::.::|.:....::.::
Zfish   618 NIAHVCGGSIINERWIVTAAHCVQDDVKIKYSQ----PGTWEVFLGLHSQKDKLTATKRLLKQVI 678

  Fly   187 RHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIF-TGWGKNSFDDPSYMNV 250
            .||.:|.....|::||:.:...:|.|..|.|:|:|:|...|.....:| :|||... :..|...|
Zfish   679 PHPYYNAYTYDNDIALMEMESPVTFSDTIRPVCLPTATDTFPAGTSVFISGWGATR-EGGSGATV 742

  Fly   251 LKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGG-EPGKDSCEGDGGSPLACAIKDNPQRYE 314
            |:|..:.::....|.|.:    |.  ::.:.:.|||. ..|.|:|:||.|.||:.   .:.:|..
Zfish   743 LQKAEVRIINSTVCNQLM----GG--QITSRMTCAGVLSGGVDACQGDSGGPLSF---PSGKRMF 798

  Fly   315 LAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            |||:|::|..|.....|.:|:||.....||
Zfish   799 LAGVVSWGDGCARRNKPGIYSNVPKFRAWI 828

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	66/239 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	66/239 (28%)
st14a	NP_001035441.2	SEA	77..168	CDD:279699
		CUB	219..322	CDD:238001
		CUB	329..431	CDD:238001
		LDLa	443..472	CDD:238060
		LDLa	474..508	CDD:238060	2/2 (100%)
		LDLa	510..544	CDD:238060	5/41 (12%)
		LDLa	550..585	CDD:238060	9/39 (23%)
		Tryp_SPc	596..828	CDD:214473	67/249 (27%)
		Tryp_SPc	597..831	CDD:238113	69/250 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910