DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Masp1

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_006248588.1	Gene:	Masp1 / 64023	RGDID:	620213	Length:	733	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	81/284 - (28%)
Similarity:	128/284 - (45%)	Gaps:	56/284 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 REEDTGLAQEAEVPWMVALLDARTS-----SYVAGGALIAPHVVITA-----RQRTEN----MTA 156
            |..:.||     .||...::...||     .:...|||::...::||     .||.:|    ::.
  Rat   459 RNAELGL-----FPWQALIVVEDTSRIPNDKWFGSGALLSESWILTAAHVLRSQRRDNTVIPVSK 518

  Fly   157 SQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMP 221
            ..:.|..|..|...|:   .:|:.....:|.||.||::|..:::|||.|:..:....|:.|||:|
  Rat   519 DHVTVYLGLHDVRDKS---GAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGAHVMPICLP 580

  Fly   222 ------SAPKNFDFSRCIFTGWGKNSFDDP-------------SYMNVLKKISLPVVQRRTCEQQ 267
                  .||....    :..|||   ..:|             :..:||:.:.||||....|:..
  Rat   581 RPEPEGPAPHMLG----LVAGWG---ISNPNVTVDEIIISGTRTLSDVLQYVKLPVVSHAECKAS 638

  Fly   268 LRLYYGNDFELDNSLMCAG-GEPGKDSCEGDGGSPLACAIKDN-PQRYELAGIVNFG--VDCGLP 328
            .....|| :.:..::.||| .|.|||:|.||.|.  |..|.|. .||:...|:|::|  .:||..
  Rat   639 YESRSGN-YSVTENMFCAGYYEGGKDTCLGDSGG--AFVIFDEMSQRWVAQGLVSWGGPEECGSK 700

  Fly   329 GVPAVYTNVANVIEWITLTTVNMP 352
            .|..|||.|:|.::|: |..:|.|
  Rat   701 QVYGVYTKVSNYVDWL-LEEMNSP 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	74/267 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	74/267 (28%)
Masp1	XP_006248588.1	CUB	33..142	CDD:238001
		FXa_inhibition	158..186	CDD:291342
		CUB	190..299	CDD:278839
		CCP	306..368	CDD:153056
		CCP	372..437	CDD:153056
		Tryp_SPc	454..715	CDD:214473	77/273 (28%)
		Tryp_SPc	455..716	CDD:238113	77/274 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910