DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and tmprss5

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	239	Identity:	71/239 - (29%)
Similarity:	113/239 - (47%)	Gaps:	31/239 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQL---VVRAGEWDFSTKTEQLPSV-- 178
            ||.|:|.  ..:.::.||::|....::||.....|....|:   ||.||     ..|..|..:
Zfish   324 PWQVSLY--YNNRHICGGSIITNQWIVTAAHCVHNYRLPQVPSWVVYAG-----IITSNLAKLAQ 381

  Fly   179 --DVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDF-----SRCIFTG 236
              ...:..|:.:..:|.....|::|||.|:..|..|..|.|:|:|    .:|.     ::|..:|
Zfish   382 YQGFAVERIIYNKNYNHRTHDNDIALVKLKTPLNFSDTIRPVCLP----QYDHDLPGGTQCWISG 442

  Fly   237 WGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGK-DSCEGDGGS 300
            ||....||.....|||:..:|::..:.|.... :|.|   |:.:.::|||...|| |:|:||.|.
Zfish   443 WGYTQPDDVLIPEVLKEAPVPLISTKKCNSSC-MYNG---EITSRMLCAGYSEGKVDACQGDSGG 503

  Fly   301 PLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            ||.|   .:...:.|.|:|::|..|..|..|.||:.||..:.||
Zfish   504 PLVC---QDENVWRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWI 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	69/237 (29%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	69/237 (29%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	69/237 (29%)
		Tryp_SPc	312..547	CDD:238113	71/239 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910