DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31780 and hspg2

DIOPT Version :9

Sequence 1:NP_723920.1 Gene:CG31780 / 318937 FlyBaseID:FBgn0051780 Length:464 Species:Drosophila melanogaster
Sequence 2:XP_021325650.1 Gene:hspg2 / 565429 ZFINID:ZDB-GENE-080807-4 Length:3701 Species:Danio rerio


Alignment Length:411 Identity:79/411 - (19%)
Similarity:128/411 - (31%) Gaps:157/411 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   134 AGGALIAPHVVITARQRTENMTASQLVVRAG---EWDFSTKTEQLPS-----------------V 178
            |||.|.:.|.|:..|.|         ::||.   ..|:....|..||                 :
Zfish  2275 AGGLLSSNHQVLETRLR---------ILRASADDTGDYICTVENGPSPQKATVSVSVTSSASLGL 2330

  Fly   179 DVPIRSIVRHPGF-----------NLENGANNVALVFLRRSLTSSRHINPICMP----------- 221
            ..||.||..|...           .:.|||..|.|.:   .||     |.:.:|           
Zfish  2331 QTPIISIEPHSAVVKQGESASFRCKVHNGAQPVRLEW---KLT-----NNLPLPDNVKVGPDSSI 2387

  Fly   222 -----SAPKNFDFSRCIFTG-WGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDN 280
                 :..||....||:.:. :|...    |.::::.:.|...|.  |....:|:..|:...|: 
Zfish  2388 MTVTNAQAKNQGTYRCVASNLYGMTH----SIVSLIVRESPKAVV--TPAGPVRVRVGDPINLE- 2445

  Fly   281 SLMC-AGGEPGK---------------------DSC---------EGDGGSPLACAIKDNPQRYE 314
               | |.|||..                     ||.         ..|.|: ..|:.::|     
Zfish  2446 ---CQAAGEPRPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGT-YVCSAQNN----- 2501

  Fly   315 LAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTTVNMPLPEEREE----VPYASPTLSAGPYLNQ 375
             .|.....|:..:.|.|.|.|               :|....||.    |..::.||....:  .
Zfish  2502 -QGTTETRVEVFVEGGPQVPT---------------VPRASVREPMIIVVEGSTATLHCDAH--G 2548

  Fly   376 WNQPNYEWLPTGYPNVNSIPWQLQEANNDLA--------NSQYVRYYPVENVGINIHSAGHGNDQ 432
            :.:|...|    :...:|:||:.:..:|.|.        :.|||           .::..|....
Zfish  2549 FPKPTITW----FKERSSLPWRHKIVDNSLILPNVGRQDSGQYV-----------CNATNHLGTS 2598

  Fly   433 QIVRPIQQDIPKDSDDLFNSV 453
            ::...::.|.|..:..|.|.|
Zfish  2599 EVTIMLEVDTPPYATSLPNDV 2619

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31780NP_723920.1 Tryp_SPc 113..344 CDD:214473 57/288 (20%)
Tryp_SPc 113..344 CDD:238113 57/288 (20%)
hspg2XP_021325650.1 SEA 84..198 CDD:321958
LDLa 216..251 CDD:238060
LDLa 277..311 CDD:238060
LDLa 317..351 CDD:238060
LDLa 360..395 CDD:238060
Ig_Perlecan_like 413..490 CDD:143220
Laminin_B 598..732 CDD:306547
EGF_Lam 766..814 CDD:238012
EGF_Lam 831..869 CDD:238012
Laminin_EGF 871..923 CDD:278482
Laminin_B 991..1125 CDD:306547
Laminin_EGF 1159..1206 CDD:278482
EGF_Lam 1208..1261 CDD:238012
Laminin_EGF 1272..1315 CDD:278482
Laminin_B 1536..1671 CDD:306547
EGF_Lam 1705..1754 CDD:238012
EGF_Lam 1755..1811 CDD:238012
IG_like 1823..1903 CDD:214653
Ig_Perlecan_like 1911..1996 CDD:143231
I-set 2025..2109 CDD:254352
I-set 2119..2231 CDD:254352
I-set 2241..2309 CDD:333254 11/42 (26%)
Ig_3 2333..2407 CDD:316449 18/81 (22%)
Ig_3 2427..2500 CDD:316449 15/79 (19%)
I-set 2517..2606 CDD:254352 20/120 (17%)
I-set 2610..2693 CDD:333254 3/10 (30%)
I-set 2699..2778 CDD:333254
I-set 2785..2867 CDD:254352
I-set 2871..2954 CDD:254352
LamG 2961..3119 CDD:238058
EGF_CA <3146..3175 CDD:238011
LamG 3226..3377 CDD:238058
EGF 3402..3433 CDD:306513
EGF_CA 3441..3470 CDD:238011
LamG 3497..3671 CDD:238058
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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