DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and AgaP_AGAP012502

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_001230484.2	Gene:	AgaP_AGAP012502 / 4578454	VectorBaseID:	AGAP012502	Length:	829	Species:	Anopheles gambiae

Alignment Length:	255	Identity:	70/255 - (27%)
Similarity:	109/255 - (42%)	Gaps:	26/255 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 TSSYVAGGALIAPHVVITARQRTENMTA--SQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGF 191
            |.::..||:||..:.::||...|::...  ...::|.|:.:.....|.....:..|..::|||.:
Mosquito    41 TVNWNCGGSLIWANFILTAAHCTKDRDTLLPPDIIRIGDLNLYDDREDALVQERTIIRVIRHPLY 105

  Fly   192 NLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIFTGWGKNSFDDPSY--MNVLKKI 254
            |..:...::||:.|...:.....:.|.|: ....|..||:....|||.:.|   .|  .|:|.|.
Mosquito   106 NTSSVFYDIALLMLNEKVNIYFEVMPTCL-WLDDNIPFSKVEAAGWGTSGF---GYGKTNILIKA 166

  Fly   255 SLPVVQRRTCEQQLRLYYGNDFELDNSLM----CAGGEPGKDSCEGDGGSPLACAIKDNPQRYE- 314
            .|.::..:.||.    ||.....:.|.||    || .:...|:|.||.|.||...:.....:..
Mosquito   167 ELKLMANKDCES----YYSQVASVKNGLMEHQLCA-WDKVMDTCPGDSGGPLQHKLIFGDYKVPF 226

  Fly   315 LAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTTVNMPLPEEREEVPYA--SPTLSAGPY 372
            |.|:.:||:.|| ...|.||..|:....||..|     |.:..|.|..|  .|...||.|
Mosquito   227 LVGVTSFGLSCG-NSQPGVYVKVSKFGSWIVET-----LQQHGERVTAAMFEPLACAGRY 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	59/223 (26%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	59/223 (26%)
AgaP_AGAP012502	XP_001230484.2	Tryp_SPc	19..258	CDD:238113	61/226 (27%)
		Tryp_SPc	19..255	CDD:214473	59/223 (26%)
		Tryp_SPc	325..>418	CDD:304450
		Trypsin	621..823	CDD:278516
		Tryp_SPc	629..826	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910