DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001025468.1	Gene:	Tmprss11c / 435845	MGIID:	3521861	Length:	431	Species:	Mus musculus

Alignment Length:	247	Identity:	76/247 - (30%)
Similarity:	120/247 - (48%)	Gaps:	34/247 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 AQEAEVPWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAG---EW----DFST 170
            |:|.|.||..:|  .:.|.:..|..||:.:.:|         ||:...:||.   :|    .|..
Mouse   206 AEEGEWPWQASL--QQNSVHRCGATLISNYWLI---------TAAHCFIRAANPKDWKVSFGFLL 259

  Fly   171 KTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNF-DFSRCIF 234
            ...|.|..   :::|:.|..::.....|::|:|.|...:....:|...|:|.|.:.| ..|..:.
Mouse   260 SKPQAPRA---VKNIIIHENYSYPAHDNDIAVVRLSSPVLYESNIRRACLPEATQKFPPNSDVVV 321

  Fly   235 TGWG--KNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGK-DSCEG 296
            ||||  |:..|.|   |:|:|..:.::..:||... :.|.|   .:...:||||...|: |:|:|
Mouse   322 TGWGTLKSDGDSP---NILQKGKVKIIDNKTCNSG-KAYGG---MITPGMMCAGFLKGRVDACQG 379

  Fly   297 DGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTT 348
            |.|.||..  :|:...:.|||||::|.:|.||..|.|||.|....:|||..|
Mouse   380 DSGGPLVS--EDSKGIWFLAGIVSWGDECALPNKPGVYTRVTYYRDWITSKT 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	72/241 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	72/241 (30%)
Tmprss11c	NP_001025468.1	SEA	62..157	CDD:279699
		Tryp_SPc	199..425	CDD:214473	72/241 (30%)
		Tryp_SPc	200..428	CDD:238113	75/244 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910