DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	289	Identity:	86/289 - (29%)
Similarity:	133/289 - (46%)	Gaps:	27/289 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 AQEAEVPWMVALLDARTSSYVAGGALI-APHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLP 176
            |...|.||.|:|.:  ...:..|..:| |..:|..|....|....:|...:||....|  ..:..
Mouse   462 AAPGEFPWQVSLRE--NHEHFCGATIIGARWLVSAAHCFNEFQDPAQWAAQAGSVHLS--GSEAS 522

  Fly   177 SVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNF-DFSRCIFTGWGKN 240
            :|...:..|.:||.::.:....:||::.|.|.|...|::.|.|:|:|...| ...:|:.:|||..
Mouse   523 AVRTRVLRIAKHPAYDADTADFDVAVLELARPLPFGRYVQPACLPAATHVFPPGKKCLISGWGYL 587

  Fly   241 SFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGK-DSCEGDGGSPLAC 304
            ..|......||:|.::.::.:..|..    .||:  .|.:.::|||...|| |||:||.|.||.|
Mouse   588 KEDFLVKPEVLQKATVELLDQSLCSS----LYGH--SLTDRMVCAGYLDGKVDSCQGDSGGPLVC 646

  Fly   305 AIKDNPQ-RYELAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTT--VNMPLPEEREEVPYASPT 366
               :.|. |:.|||||::|:.|.....|.|||.|..:.:||...|  .:||:      ||.|:|.
Mouse   647 ---EEPSGRFFLAGIVSWGIGCAEARRPGVYTRVTRLRDWILEVTSAADMPV------VPTATPA 702

  Fly   367 LSAGPYLNQWNQPNYEWLPTGYPNVNSIP 395
             .|.| ...|......|.|..:....:.|
Mouse   703 -PATP-STPWPTSPESWAPNTFAKPTAAP 729

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	71/234 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	71/234 (30%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473	71/234 (30%)
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910